20 Results for "

IL-23 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "IL-23 Antibody" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P9909
CAS No.: 815610-63-0
Synonyms: CNTO-1275; L04AC05; TT-20

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
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Cat. No.: HY-P99248
CAS No.: 1612838-76-2
Synonyms: Risankizumab rzaa; BI 655066; ABBV-066

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting IL-23 p19 subunit (Kd <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC50 = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .
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Cat. No.: HY-P9931
CAS No.: 1350289-85-8
Synonyms: CNTO 1959

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research .
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Cat. No.: HY-P99486
CAS No.: 339308-60-0
Synonyms: ABT-874

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis .
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Cat. No.: HY-P99737
CAS No.: 1884201-71-1
Synonyms: LY­3074828

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .
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Cat. No.: HY-P990217

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived anti-mouse IL-23 p19 IgG1 monoclonal antibody. Anti-Mouse IL-23 p19 Antibody (G23-8) alleviates inflammation by restoring CLDN8 expression. Anti-Mouse IL-23 p19 Antibody (G23-8) can be used for research on inflammation conditions such as colitis and asthma .
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Cat. No.: HY-P99256
CAS No.: 1326244-10-3
Synonyms: SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Tildrakizumab (SCH 900222) is a humanized anti-IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 (Kd: 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis .
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Cat. No.: HY-P99485
CAS No.: 1610353-18-8
Synonyms: AMG 139; MEDI2070

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a KD of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .
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Cat. No.: HY-P990057
CAS No.: 2622900-74-5
Synonyms: IBI-112

Target:  

Interleukin Related

Research Areas:  

Cancer

Picankibart is a human-derived IgG1κ antibody targeting IL23A. Picankibart specifically binds to the IL23 p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.
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Cat. No.: HY-P990781
CAS No.: 2415439-63-1
Synonyms: SM03
Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, IL-23) secretion and α4 integrin expression. Suciraslimab improves working memory and neuroinflammation . Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991277
Synonyms: HS-20137

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .
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Cat. No.: HY-P991274

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

BMS-986010 is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). BMS-986010 reduces IL-23-induced STAT3 phosphorylation and inhibits Th17 cell differentiation and the release of proinflammatory cytokines (such as IL-17 and TNF-α). BMS-986010 is promising for research of autoimmune diseases such as psoriasis and Crohn's disease .
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Cat. No.: HY-P991275

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CNTO4088 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). CNTO4088 is promising for research of autoimmune diseases such as psoriasis and rheumatoid arthritis .
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Cat. No.: HY-P990616

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

LY2525623 is a humanized antibody expressed in CHO targeting IL-23. LY2525623 has a huIgG1 type heavy chain and huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for LY2525623 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P810360
Synonyms: IL 23 A, IL 23, IL 23 subunit alpha, IL 23A, IL 23p19, IL-23 subunit alpha, IL-23-A, IL-23p19, IL12B, IL23

Host:  

Rabbit

Application:  

WB, IHC-P, IF-Tissue

Reactivity:  

Human

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Cat. No.: HY-P81718
Synonyms: Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P992242
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-IL-23R Antibody is a monoclonal antibody that targets IL-23R. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-23R Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P83656
Synonyms: Interleukin-23 receptor; IL23 Receptor; IL23R; IL 23R; interleukin 23 receptor; IL-23 receptor; IL23R_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P991408
DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research .
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Cat. No.: HY-P991276

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

FM-303 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). FM-303 is promising for research of immune system diseases and diseases of digestive system .
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