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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

IL-23 Antibody

" in MedChemExpress (MCE) Product Catalog:

標的別:	Interleukin Related (16) CD22 (1) IFNAR (1) Integrin (1) NOD-like Receptor (NLR) (1) TNF Receptor (1)
研究分野別:	Cancer (3) Inflammation/Immunology (16) Neurological Disease (1)

阻害剤およびアゴニスト

阻害性抗体

抗体

Targets Recommended: ADC Antibody Interleukin Related IRAK Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker Itk PROTAC-Linker Conjugates for PAC

製品番号	製品名	Target	研究分野	構造式

HY-P99248

Risankizumab Risankizumab rzaa; BI 655066; ABBV-066	Interleukin Related	Inflammation/Immunology
Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting *IL-23* p19 subunit (K_d <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC₅₀ = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .

HY-P9931

Guselkumab CNTO 1959	Interleukin Related	Inflammation/Immunology
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with K_d values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research .

HY-P9909

Ustekinumab 4 Publications Verification CNTO-1275; L04AC05; TT-20	Interleukin Related	Inflammation/Immunology Cancer
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

HY-P99486

Briakinumab ABT-874	Interleukin Related	Inflammation/Immunology
Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis .

HY-P99737

Mirikizumab LY3074828	Interleukin Related	Inflammation/Immunology
Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey *IL-23* with high affinity, with K_d values of 21 pM and 55 pM, respectively. By inhibiting the binding of *IL-23* to *IL-23R*, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .

HY-P990217

Anti-Mouse IL-23 p19 Antibody (G23-8)	Interleukin Related	Inflammation/Immunology
Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived anti-mouse IL-23 p19 IgG1 monoclonal antibody. Anti-Mouse IL-23 p19 Antibody (G23-8) alleviates inflammation by restoring CLDN8 expression. Anti-Mouse IL-23 p19 Antibody (G23-8) can be used for research on inflammation conditions such as colitis and asthma .

HY-P99256

Tildrakizumab SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody	Interleukin Related	Inflammation/Immunology Cancer
Tildrakizumab (SCH 900222) is a humanized anti-IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 (K_d: 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis .

HY-P99485

Brazikumab AMG 139; MEDI2070	Interleukin Related	Inflammation/Immunology
Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of *IL-23, with a K_D* of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .

HY-P990057

Picankibart IBI-112	Interleukin Related	Cancer
Picankibart is a human-derived IgG1κ antibody targeting *IL23A. Picankibart specifically binds to the IL23* p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.

HY-P990781

Suciraslimab SM03	CD22 NOD-like Receptor (NLR) Interleukin Related Integrin	Neurological Disease Inflammation/Immunology
Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, *IL-23) secretion and α4 integrin* expression. Suciraslimab improves working memory and neuroinflammation . Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991277

QX-004N HS-20137	Interleukin Related	Inflammation/Immunology
QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .

HY-P991274

BMS-986010	Interleukin Related	Inflammation/Immunology
BMS-986010 is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). BMS-986010 reduces IL-23-induced STAT3 phosphorylation and inhibits Th17 cell differentiation and the release of proinflammatory cytokines (such as IL-17 and TNF-α). BMS-986010 is promising for research of autoimmune diseases such as psoriasis and Crohn's disease .

HY-P991275

CNTO4088	Interleukin Related	Inflammation/Immunology
CNTO4088 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). CNTO4088 is promising for research of autoimmune diseases such as psoriasis and rheumatoid arthritis .

HY-P992242

Anti-IL-23R Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-23R Antibody is a monoclonal antibody that targets IL-23R. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-23R Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991408

DLX-105	TNF Receptor Interleukin Related IFNAR	Inflammation/Immunology
DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research .

HY-P991276

FM-303	Interleukin Related	Inflammation/Immunology
FM-303 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). FM-303 is promising for research of immune system diseases and diseases of digestive system .

製品番号	製品名	Target	研究分野	Image

HY-P99248

Risankizumab Risankizumab rzaa; BI 655066; ABBV-066	Interleukin Related	Inflammation/Immunology
Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting *IL-23* p19 subunit (K_d <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC₅₀ = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .

HY-P9931

Guselkumab CNTO 1959	Interleukin Related	Inflammation/Immunology
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with K_d values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research .

HY-P9909

Ustekinumab 4 Publications Verification CNTO-1275; L04AC05; TT-20	Interleukin Related	Inflammation/Immunology Cancer
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

HY-P99486

Briakinumab ABT-874	Interleukin Related	Inflammation/Immunology
Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis .

HY-P99737

Mirikizumab LY3074828	Interleukin Related	Inflammation/Immunology
Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey *IL-23* with high affinity, with K_d values of 21 pM and 55 pM, respectively. By inhibiting the binding of *IL-23* to *IL-23R*, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .

HY-P990217

Anti-Mouse IL-23 p19 Antibody (G23-8)	Interleukin Related	Inflammation/Immunology
Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived anti-mouse IL-23 p19 IgG1 monoclonal antibody. Anti-Mouse IL-23 p19 Antibody (G23-8) alleviates inflammation by restoring CLDN8 expression. Anti-Mouse IL-23 p19 Antibody (G23-8) can be used for research on inflammation conditions such as colitis and asthma .

HY-P99256

Tildrakizumab SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody	Interleukin Related	Inflammation/Immunology Cancer
Tildrakizumab (SCH 900222) is a humanized anti-IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 (K_d: 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis .

HY-P99485

Brazikumab AMG 139; MEDI2070	Interleukin Related	Inflammation/Immunology
Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of *IL-23, with a K_D* of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .

HY-P990057

Picankibart IBI-112	Interleukin Related	Cancer
Picankibart is a human-derived IgG1κ antibody targeting *IL23A. Picankibart specifically binds to the IL23* p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.

HY-P990781

Suciraslimab SM03	CD22 NOD-like Receptor (NLR) Interleukin Related Integrin	Neurological Disease Inflammation/Immunology
Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, *IL-23) secretion and α4 integrin* expression. Suciraslimab improves working memory and neuroinflammation . Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991277

QX-004N HS-20137	Interleukin Related	Inflammation/Immunology
QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .

HY-P991274

BMS-986010	Interleukin Related	Inflammation/Immunology
BMS-986010 is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). BMS-986010 reduces IL-23-induced STAT3 phosphorylation and inhibits Th17 cell differentiation and the release of proinflammatory cytokines (such as IL-17 and TNF-α). BMS-986010 is promising for research of autoimmune diseases such as psoriasis and Crohn's disease .

HY-P991275

CNTO4088	Interleukin Related	Inflammation/Immunology
CNTO4088 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). CNTO4088 is promising for research of autoimmune diseases such as psoriasis and rheumatoid arthritis .

HY-P990616

LY2525623	阻害性抗体	Inflammation/Immunology
LY2525623 is a humanized antibody expressed in CHO targeting *IL-23*. LY2525623 has a huIgG1 type heavy chain and huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for LY2525623 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992242

Anti-IL-23R Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-23R Antibody is a monoclonal antibody that targets IL-23R. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-23R Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991408

DLX-105	TNF Receptor Interleukin Related IFNAR	Inflammation/Immunology
DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research .

HY-P991276

FM-303	Interleukin Related	Inflammation/Immunology
FM-303 is a monoclonal antibody inhibitor targeting interleukin-23 (IL-23). FM-303 is promising for research of immune system diseases and diseases of digestive system .

Host:	Rabbit (3)
Reactivity:	Human (3)
Application:	IHC-P (2) IF-Tissue (1) WB (3)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (1) Monoclonal (2) Recombinant (2)
Modification:	Unmodified (3)

製品番号	Compare	製品名	Application	Reactivity	Image

HY-P810360

	IL-23 alpha Antibody (YA9682) IL 23 A, IL 23, IL 23 subunit alpha, IL 23A, IL 23p19, IL-23 subunit alpha, IL-23-A, IL-23p19, IL12B, IL23	WB, IHC-P, IF-Tissue	Human
	IL-23 alpha Antibody (YA9682) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to IL-23 alpha.

HY-P81718

	IL-23 alpha Antibody (YA1463) Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19	WB	Human
	IL-23 alpha Antibody (YA1463) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-23 alpha.

HY-P83656

	**IL-23R Antibody** Interleukin-23 receptor; IL23 Receptor; IL23R; IL 23R; interleukin 23 receptor; IL-23 receptor; IL23R_HUMAN.	WB, IHC-P	Human
	IL-23R Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IL-23R.

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