1. Immunology/Inflammation
  2. Interleukin Related
  3. Briakinumab

Briakinumab  (Synonyms: ABT-874)

Cat. No.: HY-P99486 Purity: ≥95.0%
COA

Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis.

For research use only. We do not sell to patients.

Briakinumab Chemical Structure

Briakinumab Chemical Structure

CAS No. : 339308-60-0

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1 mg USD 350 In-stock
5 mg USD 910 In-stock
10 mg USD 1460 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis[1].

IC50 & Target[1]

IL-12

 

IL-23

 

In Vitro

Briakinumab targets the p40 molecule shared by interleukin-12 and interleukin-23[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Briakinumab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Purity: ≥95.0%

References
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Briakinumab Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Briakinumab
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HY-P99486
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