1 Result for "

KRAS G12V/RAF1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRAS G12V/RAF1" in MCE Product Catalog:

Cat. No.: HY-164365
CAS No.: 3043670-74-9
Target:  

PROTACs Ras

Research Areas:  

Cancer

PROTAC K-Ras degrader-2 (compound 48) is a KRAS G12V PROTAC degrader with an IC50 of 20-200 nM for KRAS G12V/RAF1. PROTAC K-Ras degrader-2 degrades SW620 KRAS G12V with a DC50 of 1-10 nM. PROTAC K-Ras degrader-2 inhibits cell growth of SW620 3D cell with an IC50 of ≤10 nM. PROTAC K-Ras degrader-2 can be used for the study of colorectal cancer (CRC) .
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