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Results for "

LAT-1 (SLC7A5)

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

3

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120139
    KMH-233
    1 Publications Verification

    		 Amino acid Transporter Cancer
    KMH-233, a potent, reversible and selective inhibitor of l-type amino acid transporter LAT1/SLC7A5, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM) .
    KMH-233
  • HY-183513
    L-Ala-BPA

    		FAP Cancer
    L-Ala-BPA is a boron delivery agent. L-Ala-BPA is transported into tumor cells via PEPT1/2 and LAT-1 (SLC7A5) pathways and is rapidly cleaved systemically by endogenous proteases including FAP to yield L-BPA (HY-W087830). L-Ala-BPA shows antitumor activity and can be used for the research of Boron Neutron Capture Therapy (BNCT) .
    L-Ala-BPA
  • HY-W267524
    H-Phe(3-CF3)-OH

    		Drug Derivative Cancer
    H-Phe (3-CF3)-OH is a phenylalanine derivative targeting the L-type amino acid transporter 1 (LAT1, SLC7A5) as its core target, and it belongs to LAT1 substrates. H-Phe (3-CF3)-OH can be used for prodrug scaffold development and research related to multiple solid tumors .
    H-Phe(3-CF3)-OH

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