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MG-132 (GMP)

" in MedChemExpress (MCE) Product Catalog:
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MG-132 (GMP)
MG-132 (GMP)
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Cat. No.: HY-13259G
CAS No.: 133407-82-6
Synonyms: Z-Leu-Leu-Leu-al (GMP)
MG-132 (GMP) (Z-Leu-Leu-Leu-al (GMP)) is MG-132 (HY-13259) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .
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