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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Metal chelate ligand
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Metal chelate ligand" in MCE Product Catalog:
Cat. No.: HY-W047709
CAS No.: 140-07-8
Synonyms: THEED; THEEN
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (THEED; THEEN) is a tetrapodal pentadentate chelating ligand that functions as a chelator to form stable complexes with metal ions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine serves as a versatile building block for organic synthesis, a reagent for metal extraction, and an auxiliary for catalytic reactions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine-derived metal complexes exhibit antibacterial, antifungal, and anticancer activities. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine and its metal complexes can be used for research related to breast cancer, leukemia, various bacterial and fungal infections .
Cat. No.: HY-W034674
CAS No.: 1470-61-7
Synonyms: Silver(1+) diethyldithiocarbamate
Cat. No.: HY-W007317
CAS No.: 578-66-5
Research Areas:
8-Aminoquinoline is a chelating ligand and intermediate. 8-Aminoquinoline assists metal-catalyzed direct C (sp 2)-H and unactivated C (sp 3)-H bond functionalization, copper-mediated C-H/C-H coupling, as well as copper/silver-catalyzed aryl C (sp 2)-H amination reactions. 8-Aminoquinoline forms cationic Pt (II) complexes with anti-tumor activity. 8-Aminoquinoline is used in research related to latent malaria, glioblastoma, pancreatic adenocarcinoma, adenocarcinoma and biphasic mesothelioma .
Cat. No.: HY-120420
CAS No.: 167695-87-6
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N4Py is a bleomycin-mimetic pentadentate ligand that targets intracellular FeII and reversibly chelates a variety of transition metals. N4Py chelates induce apoptosis through two pathways: DNA cleavage via ROS generation and XIAP downregulation via ZnII chelation, with only FeII/FeIII-N4Py exhibiting potent DNA cleavage activity. The folate conjugate of N4Py targets folate receptors, can be intracellularly cleaved, and selectively kills FR-positive cancer cells. N4Py can be used in research on various cancers including nasopharyngeal epidermoid carcinoma, ovarian cancer, and mammary adenocarcinoma .
Cat. No.: HY-164854
CAS No.: 914639-15-9
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(R)-DOTAGA2 (Compound 7) is a metal chelate ligand. (R)-DOTAGA2 can be used to evaluate blood volume changes in the heart and brain .
Cat. No.: HY-181597
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LINS05414 is a histamine H3 receptor ligand with antiCholinesterase and metal chelating activities. LINS05414 exhibits inhibitory activity against acetylcholinesterase (pIC50 = 4.03) and butyrylcholinesterase (pIC50 = 3.83), with a pKi of 6.37 for human histamine H3 receptors. LINS05414 chelates copper ions, ferrous ions and ferric ions. LINS05414 regulates the release of neurotransmitters. LINS05414 can be used in the research of neurodegenerative diseases .
Cat. No.: HY-185401A
CAS No.: 191486-46-1
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(E,E)-ATSM is a chelating agent. (E,E)-ATSM can react with the metallized ligand Copper gluconate. (E,E)-ATSM can be used in research on central nervous system diseases .
Cat. No.: HY-156939
CAS No.: 65229-17-6
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ZnDTPA is an orally effective chelating agent, which belongs to the class of amino carboxylic acid chelating agents and is mainly used to form stable complexes with metal ions. DTPA (diethylenetriaminepentaacetic acid) itself is a polydentate ligand that can form stable cyclic or chain-like complexes with a variety of metal ions. ZnDTPA can be used to reduce the long-term toxicity of 239Pu to rats and reduce the incidence of osteosarcoma, breast cancer, etc. in rats .
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Methyl dithiocarbazate (S-Methyldithiocarbazate; SMDTC; NSC 4423) is a dithiocarbazate derivative, which is commonly used as a Schiff base ligand precursor to construct NS/SNS-type chelate complexes with transition metals (Zn 2+, Ni 2+, Cu 2+, etc.) .
Cat. No.: HY-K0256
MCE Chelating Agarose (IDA) 6FF is prepared by covalently coupling tridentate iminodiacetic acid (IDA) to an agarose matrix. It features high binding capacity, excellent specificity, and superior ligand stability. The resin allows flexible chelation with metal ions such as Zn2+, Ni2+, or Cu2+, and is suitable for the purification of His-tagged recombinant proteins expressed in bacterial, mammalian, insect, and baculovirus systems.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
