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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Methyl substitution
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Methyl substitution" in MCE Product Catalog:
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1 Cited Publications
Synonyms: Acetoacetate Methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate
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Cat. No.: HY-163032
CAS No.: 3053862-47-5
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 Ki = 25 ± 3 a nM, FABP3 Ki = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease .
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2,2-Dihydroxy-1-phenylethan-1-one (Phenylglyoxal hydrate) is a phenylglyoxal-based, antioxidant drug synthesis intermediate. 2,2-Dihydroxy-1-phenylethan-1-one serves as a starting material for the synthesis of aromatic amines or aliphatic amines. It can be used to synthesize polysubstituted pyrrolo[3,2-c]pyridin-4-one derivatives, and also acts as a key structural unit in the microwave-assisted cascade synthesis of substituted 2-methyl-7-aryl-6H-thiazoloindole compounds .
Cat. No.: HY-W014159
CAS No.: 55289-35-5
Cat. No.: HY-41494S1
CAS No.: 70838-82-3
Cat. No.: HY-41494S
CAS No.: 207742-73-2
Synonyms: 2-Methylbenzoic acid-d7
Cat. No.: HY-W598198
CAS No.: 40139-55-7
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Ethyl 3-azidopropanoate comprises an ethyl ester and a terminal azide group with a 2-carbon linker. The azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The methyl ester groups can be hydrolyzed, reduced, or substituted under different conditions.
Cat. No.: HY-116654
CAS No.: 71868-10-5
Synonyms: Caccure 907; photoinitiator907
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2-Methyl-4'-(methylthio)-2-morpholinopropiophenone (Caccure 907) is structurally characterized as a substituted drug derivative.
Cat. No.: HY-177787A
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2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
Cat. No.: HY-W001297
CAS No.: 1121-79-5
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3-Chloro-6-methylpyridazine is a substituted pyridazine derivative containing an electron-withdrawing chlorine atom and an electron-donating methyl group. Pyridazine compounds generally possess pharmacological activities such as antibacterial and anti-inflammatory properties. 3-Chloro-6-methylpyridazine can serve as an organic ligand for constructing organic-inorganic hybrid chloroantimonate materials with semiconducting behavior. 3-Chloro-6-methylpyridazine can be used in studies related to optoelectronic devices, photodetectors, and photocatalysis .
10-Methyl lauric acid (10-Methyl dodecanoic acid) is a alkyl-substituted fatty acid. 10-Methyl lauric acid can be found in the Gram-positive bacteria B. acetylicum, as well as the mandibular gland secretions of carpenter ant species .
Cat. No.: HY-158937
CAS No.: 35700-22-2
Synonyms: 15(R)-Methyl carboprost; 15(R)-15-Methyl PGF2α Methyl ester
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15(R)-15-Methyl prostaglandin F2α methyl ester (15(R)-Methyl carboprost) (compound 15R) is a 15-methyl substituted prostaglandin analog, a member of the prostaglandin family, with potential biological activities in a variety of biological systems, but its specific activity mechanism and application details are not described in detail from the existing information.
Cat. No.: HY-129661
CAS No.: 763023-14-9
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AH 7959 is an orally active N-substituted cyclohexyl methyl benzamide compound that has analgesic effects, the oral and subcutaneous ED50 of AH 7959 in mice is greater than 100 mg/kg .
Cat. No.: HY-W140555
CAS No.: 3465-69-8
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5,7-Dimethoxyphthalide, a dimethoxy derivative of phthalide, can undergo nucleophilic substitution reactions with functionalized long-chain alkyl iodides. 5,7-Dimethoxyphthalide acts as a synthetic building block to prepare anti-Helicobacter pylori products including CJ molecule and sporotricale methyl ether. 5,7-Dimethoxyphthalide can be utilized for relevant researches on Helicobacter pylori infection and structure-activity relationship (SAR) .
Cat. No.: HY-W399914
CAS No.: 52221-08-6
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tert-Butyl methyl adipate is a linker with an methyl ester group and a t-butyl ester. The methyl ester groups can be hydrolyzed, reduced, or substituted under different conditions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Cat. No.: HY-W800661
CAS No.: 2468714-93-2
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Tos-PEG3-methyl ester is a PEG linker with tosyl and methyl ester moieties. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound. Methyl ester can be hydrolyzed under strong basic condition.
Cat. No.: HY-W800662
CAS No.: 2468714-95-4
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Bromo-PEG2-methyl ester is a PEG linker containing a bromide moiety and a methyl ester. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Methyl ester can be hydrolyzed under strong basic condition.
Cat. No.: HY-208559
CAS No.: 169609-85-2
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Insecticidal agent 36 is an insecticidal N-(substituted arylmethyl)-4-[bis (substituted phenyl) methyl]piperidine, or its corresponding N-oxide or agriculturally acceptable salt. Insecticidal agent 36 exhibits insecticidal activity, with a growth inhibition rate of 95% at a concentration of 100 µM and a pI50 value of 5.1. Insecticidal agent 36 can be used in pest control research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
