105-45-3
105-45-3
Chemical Structure
Methyl acetylacetate
Synonym(s): Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate
- CAS No.: 105-45-3
- Formula:C5H8O3
- Molecular Weight:116.12
IUPAC Name: methyl 3-oxobutanoate
InChIKey: WRQNANDWMGAFTP-UHFFFAOYSA-N
SMILES: CC(CC(OC)=O)=O
Biological Activity: Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methyl acetylacetate | 99.86% | Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases. | ||||||||||||||||||||
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Methyl acetylacetate (Standard) | ≥98% | Methyl acetylacetate (Standard) is the analytical standard of Methyl acetylacetate. This product is intended for research and analytical applications. Methyl acetylacetate is an endogenous metabolite. | ||||||||||||||||||||
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Methyl acetylacetate-d3 | 95.0% | Methyl acetylacetate-d3 (Acetoacetate methyl ester-d3) is a deuterium labeled Methyl acetylacetate (HY-Y1298). Methyl acetylacetate is an endogenous metabolite. | ||||||||||||||||||||
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Acetoacetic acid sodium | 98.0% | Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases. | ||||||||||||||||||||
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Methyl levulinate (Standard) | ≥98% | Methyl levulinate (Standard) (Methyl β-acetylpropionate (Standard)) is the analytical standard of Methyl levulinate (HY-N3272). This product is intended for research and analytical applications. Methyl levulinate (NSC 24874) is a Alkaloids product that can be isolated from the stems and leaves of Ervatamia hainanensis.. | ||||||||||||||||||||
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Methyl 3-oxopentanoate | Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions. | |||||||||||||||||||||
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Ethyl acetoacetate (Standard) | ≥98% | Ethyl acetoacetate (Standard) is the analytical standard of Ethyl acetoacetate. This product is intended for research and analytical applications. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. | ||||||||||||||||||||
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Ethyl acetoacetate-13C2 | Ethyl acetoacetate-13C2 (Ethyl acetylacetate-13C2) is the 13C-labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. | |||||||||||||||||||||
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Ethyl acetoacetate-13C4 | Ethyl acetoacetate-13C4 is the 13C labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. | |||||||||||||||||||||
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Ethyl acetoacetate-13C | 98.6% | Ethyl acetoacetate-13C is the 13C labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. | ||||||||||||||||||||
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Methyl acetylacetate-13C4 | Methyl acetylacetate-13C4 is an isotopically labeled compound. Methyl acetylacetate-13C4 can be used for various biochemical studies. | |||||||||||||||||||||
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Dimethyl malonate | 99.92% | Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis. | ||||||||||||||||||||
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References
- [1]. Folkendt M M, et al. Gas-phase proton NMR studies of keto-enol tautomerism of acetylacetone, methyl acetoacetate, and ethyl acetoacetate. The Journal of Physical Chemistry, 1985, 89(15): 3347-3352.
- [2]. Api AM, et al. RIFM fragrance ingredient safety assessment, methyl acetoacetate, CAS Registry Number 105-45-3. Food Chem Toxicol. 2019 Dec;134 Suppl 1:110615. [Content Brief]
- [3]. Tozkoparan B, et al. Synthesis and anti-inflammatory activities of some thiazolo[3,2-a]pyrimidine derivatives. Farmaco. 1999 Sep 30;54(9):588-93. [Content Brief]
