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Morus alba L.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (3) Endogenous Metabolite (1)
By Research Areas:	Cancer (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113418

Beta-Cortol	Endogenous Metabolite	Cancer
Beta-Cortol is an O-glycosylated compound and cortisol metabolite. It can be isolated from the leaves of mulberry cultivar Yu 711, and its concentration decreases significantly when the plant is subjected to drought stress. Beta-Cortol serves as a biomarker, as serum Beta-Cortol levels in early non-small cell lung cancer models are downregulated to 1/8 of the preoperative level after tumor resection. Due to such dramatic changes under specific pathological conditions, Beta-Cortol is currently widely used in studies related to early non-small cell lung cancer .

HY-N10407

Quercetin 3-O-rutinoside-7-O-glucoside	Drug Derivative	Others
Quercetin 3-O-rutinoside-7-O-glucoside is a flavonol glycoside and a derivative of Quercetin (HY-18085). Quercetin 3-O-rutinoside-7-O-glucoside can be isolated from the leaves and fruits of Korean Morus alba L. as well as the leaves of Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside inhibits lipid peroxidation in large unilamellar vesicles in vitro. Quercetin 3-O-rutinoside-7-O-glucoside possesses antioxidant activity .

HY-N16130

Kuwanon S	Drug Derivative	Others
Kuwanon S is a flavonoid compound that can be isolated from the root bark of Morus alba L. Kuwanon S is commonly used in organic synthesis and biochemistry experiments .

HY-N1324

Sanggenon N	Others	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

HY-N17552

Notabilisin L	Others	Cancer
Notabilisin L is an isoprenylated flavonoid. Notabilisin L can be isolated from root bark of M. alba. Notabilisin L has no significant inhibitory effects on the viability of gastric cancer cells .

HY-N16844

Steppogenin-5'-C-β-D-glucopyranoside	Drug Derivative	Others
Steppogenin-5'-C-β-D-glucopyranoside is a natural flavonoid.

Beta-Cortol	Structural Classification Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite
Beta-Cortol is an O-glycosylated compound and cortisol metabolite. It can be isolated from the leaves of mulberry cultivar Yu 711, and its concentration decreases significantly when the plant is subjected to drought stress. Beta-Cortol serves as a biomarker, as serum Beta-Cortol levels in early non-small cell lung cancer models are downregulated to 1/8 of the preoperative level after tumor resection. Due to such dramatic changes under specific pathological conditions, Beta-Cortol is currently widely used in studies related to early non-small cell lung cancer .

Kuwanon S	Structural Classification Flavonoids Flavones Plants Moraceae Morus alba Linn. Source Classification	Drug Derivative
Kuwanon S is a flavonoid compound that can be isolated from the root bark of Morus alba L. Kuwanon S is commonly used in organic synthesis and biochemistry experiments .

Sanggenon N	Flavanonols Flavonoids Phenols Polyphenols Plants Moraceae Source Classification Morus alba Linn.	Others
Sanggenon N is an isoprenylated flavonoid that can be isolated from the root bark of Morus alba.Sanggenon N has hepatoprotective activities on t-BHP-induced cell cytotoxicity in HepG2 cells with an EC₅₀ of 23.45 μM .

Notabilisin L	Structural Classification Morus notabilis C. K. Schneid. Phenols Polyphenols Plants Moraceae Source Classification	Others
Notabilisin L is an isoprenylated flavonoid. Notabilisin L can be isolated from root bark of M. alba. Notabilisin L has no significant inhibitory effects on the viability of gastric cancer cells .

Steppogenin-5'-C-β-D-glucopyranoside	Structural Classification Flavonoids Flavonones Plants Moraceae Morus alba Linn. Source Classification	Drug Derivative
Steppogenin-5'-C-β-D-glucopyranoside is a natural flavonoid.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Morus alba L.

Inhibitors & Agonists

NaturalProducts

Natural
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