Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
MrgX2 receptor
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "MrgX2 receptor" in MCE Product Catalog:
9
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P3419
CAS No.: 929905-12-4
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P702380
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MRGPRX2; MAS-Related GPR, Member X2; MAS Related GPR Family Member X2; Mas-Related G Protein-Coupled receptor G3; MrgX2; G Protein-Coupled receptor MrgX2; Mas-Related G-Protein Coupled receptor Member X2; MGRG3
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-176446
CAS No.: 2641397-91-1
Research Areas:
Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of MrgX2 receptor with an IC50 value of 0.042-2.5 nM. Mrgx2 antagonist-3 blocks downstream G protein signaling and β-Arrestin recruitment, thereby inhibiting MrgX2 receptor-mediated calcium influx and cellular degranulation. Mrgx2 antagonist-3 is promising for research of inflammation-related diseases and pruritus, such as chronic urticaria, allergic asthma .
Cat. No.: HY-P87425A
Synonyms: MrgX2, MRGPRX2, Mas-related G-protein coupled receptor member X2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
