2641397-91-1
2641397-91-1
Chemical Structure
Mrgx2 antagonist-3
- CAS No.: 2641397-91-1
- Formula:C15H15F2N3O
- Molecular Weight:291.30
SMILES: O=C1C(CC)=C(C(C)C)N=C2NC3=CC(F)=C(C=C3N12)F
Biological Activity: Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of MrgX2 receptor with an IC50 value of 0.042-2.5 nM. Mrgx2 antagonist-3 blocks downstream G protein signaling and β-Arrestin recruitment, thereby inhibiting MrgX2 receptor-mediated calcium influx and cellular degranulation. Mrgx2 antagonist-3 is promising for research of inflammation-related diseases and pruritus, such as chronic urticaria, allergic asthma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mrgx2 antagonist-3 | 98.24% | Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of MrgX2 receptor with an IC50 value of 0.042-2.5 nM. Mrgx2 antagonist-3 blocks downstream G protein signaling and β-Arrestin recruitment, thereby inhibiting MrgX2 receptor-mediated calcium influx and cellular degranulation. Mrgx2 antagonist-3 is promising for research of inflammation-related diseases and pruritus, such as chronic urticaria, allergic asthma. | ||||||||||||||||||||
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References
Keywords
