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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
N-Arachidonyldopamine
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "N-Arachidonyldopamine" in MCE Product Catalog:
Research Areas:
N-Arachidonyldopamine acts as an Anandamide (HY-10863) membrane transport inhibitor, a selective CB1 cannabinoid receptor agonist, and a VR1 receptor activator. It exhibits an EC50 value of 48 nM for rat VR1 and a Ki value of 0.25 μM for CB1. N-Arachidonyldopamine exists in mammalian neural tissues. It stimulates intracellular Ca 2+ mobilization, mediates cannabinoid-like effects, and induces hypothermia, hypomotility, catalepsy, analgesia, and hyperalgesia to heat. N-Arachidonyldopamine possesses anticancer activity against breast cancer. It can be used in research related to breast cancer and heat hyperalgesia .
Cat. No.: HY-110018R
CAS No.: 199875-69-9
Research Areas:
N-Arachidonyldopamine (Standard) is the analytical standard of N-Arachidonyldopamine (HY-110018). This product is intended for research and analytical applications. N-Arachidonyldopamine is a potent and selective endogenous CB1 receptor agonist with a Ki of 250 nM . N-Arachidonyldopamine is also a potent and selective TRPV1 agonist an with EC50 of ~ 50 nM .
Cat. No.: HY-110018S
CAS No.: 1159908-42-5
Cat. No.: HY-114583
CAS No.: 1041478-78-7
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Research Areas:
AMG-8562 is a selective, orally active transient receptor potential vanilloid 1 (TRPV1) modulator that inhibits the activation of rat TRPV1 by Capsaicin (HY-10448), Anandamide (HY-10863) and N-arachidonyldopamine (HY-110018), with IC50 values of 1.75, 9.29 and 3.87 nM, respectively. AMG-8562 blocks capsaicin-induced activation, potentiates pH5-induced activation and has no effect on heat-induced activation of rat TRPV1, whereas it completely blocks capsaicin- and heat-induced activation and partially blocks pH5-induced activation of human TRPV1. AMG-8562 can be used in studies of TRPV1 activation patterns, hyperalgesia and pain-related research .
Cat. No.: HY-P11504
CAS No.: 3109821-26-0
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
