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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
NEGR-1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "NEGR-1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P76508
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NEGR1; A Kindred Of IgLON; Neuronal Growth Regulator 1; Neurotractin; IGLON4; MGC46680; IgLON Family Member 4; Alternative Protein NEGR1; KILON; DMML2433; Ntra
Species:
Human
Source:
HEK293
Cat. No.: HY-RS09186
Target:
Research Areas:
NEGR1 Human Pre-designed siRNA Set A contains three designed siRNAs for NEGR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18671
Target:
Research Areas:
Negr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Negr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25157
Target:
Research Areas:
Negr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Negr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150286A
CAS No.: 2715974-36-8
Target:
Research Areas:
(R)-SM875 is a cellular prion protein (PrP) degrader with an IC50 of 3 μM in HEK293 cells. (R)-SM875 interacts with PrP folding intermediates, binds to a binding pocket unique to FI-PrP, inhibits PrP C maturation, blocks prion replication, and induces cytotoxicity, autophagy, PrP C aggregation, as well as lysosome-dependent autophagy-mediated post-translational degradation of PrP C, without altering the mRNA level of PrP C. (R)-SM875 can be used in research related to prion diseases [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
