Kilon/NEGR1 Protein, Mouse (HEK293, His)

The Kilon/NEGR1 protein has been implicated in cell adhesion, suggesting a role in important cellular interactions. Its potential function as a transneuronal growth-promoting factor highlights its dynamic role in promoting regenerative axonal sprouting in the mammalian brain. Kilon/NEGR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kilon/NEGR1 protein, expressed by HEK293 , with C-His labeled tag.

Kilon/NEGR1 Protein emerges as a potential participant in cell adhesion, suggesting a role in mediating crucial interactions for cellular processes. Additionally, its potential function as a trans-neural growth-promoting factor highlights its dynamic role in facilitating regenerative axon sprouting in the mammalian brain. The proposed involvement of Kilon/NEGR1 in regenerative processes implies its significance in promoting axon growth, particularly in the context of neural regeneration within the brain. Exploring the specific mechanisms through which Kilon/NEGR1 contributes to cell adhesion and facilitates regenerative axon sprouting may offer valuable insights into its role in neural development and regeneration. Further investigation into Kilon/NEGR1's functions could deepen our understanding of its potential implications in neuronal plasticity and regenerative processes in the mammalian brain.

Mouse

HEK293

C-His

Q80Z24/NP_001034183.1 (V32-G318)

320840  [NCBI]

Full Length of Mature Protein

VDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG

Approximately 43-55 kDa due to the glycosylation

• 
  ≥ 90%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.