Kilon/NEGR1 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
The Kilon/NEGR1 protein has been implicated in cell adhesion, suggesting a role in important cellular interactions. Its potential function as a transneuronal growth-promoting factor highlights its dynamic role in promoting regenerative axonal sprouting in the mammalian brain. Kilon/NEGR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kilon/NEGR1 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
The Kilon/NEGR1 protein has been implicated in cell adhesion, suggesting a role in important cellular interactions. Its potential function as a transneuronal growth-promoting factor highlights its dynamic role in promoting regenerative axonal sprouting in the mammalian brain. Kilon/NEGR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kilon/NEGR1 protein, expressed by HEK293 , with C-His labeled tag.
Background
Kilon/NEGR1 Protein emerges as a potential participant in cell adhesion, suggesting a role in mediating crucial interactions for cellular processes. Additionally, its potential function as a trans-neural growth-promoting factor highlights its dynamic role in facilitating regenerative axon sprouting in the mammalian brain. The proposed involvement of Kilon/NEGR1 in regenerative processes implies its significance in promoting axon growth, particularly in the context of neural regeneration within the brain. Exploring the specific mechanisms through which Kilon/NEGR1 contributes to cell adhesion and facilitates regenerative axon sprouting may offer valuable insights into its role in neural development and regeneration. Further investigation into Kilon/NEGR1's functions could deepen our understanding of its potential implications in neuronal plasticity and regenerative processes in the mammalian brain.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-His
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Accession
Q80Z24/NP_001034183.1 (V32-G318)
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Molecular Construction
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N-term
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Kilon (V32-G318)
Accession # Q80Z24/NP_001034183.1 -
His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
NEGR1; A Kindred Of IgLON; Neuronal Growth Regulator 1; Neurotractin; IGLON4; MGC46680; IgLON Family Member 4; Alternative Protein NEGR1; KILON; DMML2433; Ntra
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AA Sequence
VDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG
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Molecular Weight
Approximately 47 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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