Negr1 - neuronal growth regulator 1 Gene

Also Known as Ntra; KILON; 5330422G01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320840

Summary

Acts upstream of or within several processes, including feeding behavior; locomotory behavior; and positive regulation of neuron projection development. Located in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human NEGR1 (neuronal growth regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Negr1 Products (2)

mRNA Protein Name
NM_001039094.3 NP_001034183.1 neuronal growth regulator 1 isoform a precursor
NM_177274.4 NP_796248.1 neuronal growth regulator 1 isoform b precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
30932003 MGI
acts upstream of or within cell-cell adhesion IDA
IDA: Inferred from direct assay
22844493 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
27940359 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
31086253 MGI
acts upstream of or within feeding behavior IMP
IMP: Inferred from mutant phenotype
22844493 MGI
acts upstream of or within lipid droplet formation IMP
IMP: Inferred from mutant phenotype
31086253 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
22844493 MGI
acts upstream of neuron projection development IDA
IDA: Inferred from direct assay
22844493 MGI
acts upstream of or within neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
30932003 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IMP
IMP: Inferred from mutant phenotype
37216094 MGI
acts upstream of or within positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
22844493 MGI
acts upstream of or within positive regulation of saliva secretion IMP
IMP: Inferred from mutant phenotype
37216094 MGI
acts upstream of or within skeletal muscle organ development IMP
IMP: Inferred from mutant phenotype
31086253 MGI
acts upstream of or within social behavior IMP
IMP: Inferred from mutant phenotype
30932003 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
22844493 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal growth regulator 1

  • kindred of IgLON

  • neurotractin

Recombinant Negr1 Proteins

Cat. No. Product Name Accession Purity
HY-P75934 Kilon/NEGR1 Protein, Mouse (HEK293, His) Q80Z24/NP_001034183.1 (V32-G318) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09186 NEGR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18671 Negr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25157 Negr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Negr1 NCBI NCBI:257194