11 Results for "

NHEK

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "NHEK" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113509
CAS No.: 89663-86-5
Purity:  98.0%
Synonyms: LXA4
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM .
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Cat. No.: HY-B0633C
CAS No.: 9004-61-9
Hyaluronic acid (Mw: 1000-2000 Da) is a long-chain unbranched polysaccharide with a molecular weight of 1000-2000 Da. Hyaluronic acid (Mw: 2000 Da) inhibits IL-1β expression and increases LC3-II. Hyaluronic acid (Mw: 1000-2000Da) can regulate tissue homeostasis and stress resistance, promote angiogenesis and tissue remodeling. Hyaluronic acid (Mw: 1000-2000 Da) has good biocompatibility and biodegradability, and can be used in drug delivery systems and tissue engineering. Hyaluronic acid (Mw: 2000 Da) can reduce facial skin blemishes and sagging .
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Cat. No.: HY-W011309
CAS No.: 6145-69-3
Synonyms: 1-O-HDG; HXDG
Target:  

PPAR PGE synthase

Research Areas:  

Inflammation/Immunology

1-O-Hexadecylglycerol can up-regulate PPAR-γ expression, inhibit pGE2, and exhibit anti-inflammatory properties . 1-O-Hexadecylglycerol is effective in oral administration .
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Cat. No.: HY-178226
CAS No.: 3003834-34-9
PBX-7016 is a DNA topoisomerase I inhibitor and DDX5 degrader. PBX-7016 induces DNA damage and downregulates Survivin, Mcl-1, and XIAP. PBX-7016 exerts a bystander killing effect. PBX-7016 can serve as an ADC payload for the synthesis of ADC. PBX-7016 is applicable to research related to head and neck cancer, non-small cell lung cancer, breast cancer, colorectal cancer, and ovarian cancer .
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Cat. No.: HY-167740
CAS No.: 425642-33-7
Synonyms: GroPIns (lysine)
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Glycerophosphoinositol (GroPIns) lysine is a phospholipid metabolite that possesses anti-dandruff, anti-inflammatory, and anti-aging activities; it significantly suppresses UVB-induced PGE secretion in NHEK keratinocytes.
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Cat. No.: HY-111378
CAS No.: 863598-09-8
Purity:  ≥98.0%
Target:  

Casein Kinase

Research Areas:  

Metabolic Disease

Casein Kinase II Inhibitor IV is a potent, ATP-competitive of casein kinase II inhibitor with an IC50 of 9 nM. Casein Kinase II Inhibitor IV ia also a human keratinocytes (NHEK) differentiation inducer .
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Cat. No.: HY-113509S
CAS No.: 1622429-53-1
Synonyms: LXA4-d5
Lipoxin A4-d5 is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM .
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Cat. No.: HY-172148
CAS No.: 2641132-66-1
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid (HY-Y0520) that efficiently delivers the active ingredient Itaconic acid to skin tissue following oral administration. Itaconic acid prodrug-1 possesses immunomodulatory properties, significantly inhibiting Poly(I:C)/IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 can be utilized for the research of alopecia areata and other inflammatory skin diseases .
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Cat. No.: HY-111378R
CAS No.: 863598-09-8
Research Areas:  

Metabolic Disease

Casein Kinase II Inhibitor IV (Standard) is the analytical standard of Casein Kinase II Inhibitor IV (HY-111378). This product is intended for research and analytical applications. Casein Kinase II Inhibitor IV is a potent, ATP-competitive of casein Kinase II inhibitor with an IC50 of 9 nM. Casein Kinase II Inhibitor IV ia also a human keratinocytes (NHEK) differentiation inducer .
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Cat. No.: HY-W344383A
Research Areas:  

Others

Boc-Phe-Ser-Arg-AMC TFA is a fluorescence peptide substrate with specificity. Boc-Phe-Ser-Arg-AMC TFA can be cleaved by tryptase-like serine proteases (TLSPs) to generate fluorescent products, thereby enabling the detection of TLSPs activity. Boc-Phe-Ser-Arg-AMC TFA can be used in studies related to rosacea .
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Cat. No.: HY-W344383
CAS No.: 73554-90-2
Research Areas:  

Others

Boc-Phe-Ser-Arg-AMC is a fluorescence peptide substrate with specificity. Boc-Phe-Ser-Arg-AMC can be cleaved by tryptase-like serine proteases (TLSPs) to generate fluorescent products, thereby enabling the detection of TLSPs activity. Boc-Phe-Ser-Arg-AMC can be used in studies related to rosacea .
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