73554-90-2
73554-90-2
Chemical Structure
Boc-Phe-Ser-Arg-AMC
- CAS No.: 73554-90-2
- Formula:C33H43N7O8
- Molecular Weight:665.74
IUPAC Name: ethyl 5-amino-1H-pyrrole-2-carboxylate
InChIKey: JLKJMNJZJBEYLQ-SDHOMARFSA-N
SMILES: CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC(OC(C)(C)C)=O)CC2=CC=CC=C2)=O)=O)=O)C=C1O3)=CC3=O
Biological Activity: Boc-Phe-Ser-Arg-AMC is a fluorescence peptide substrate with specificity. Boc-Phe-Ser-Arg-AMC can be cleaved by tryptase-like serine proteases (TLSPs) to generate fluorescent products, thereby enabling the detection of TLSPs activity. Boc-Phe-Ser-Arg-AMC can be used in studies related to rosacea[1][2].
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Boc-Phe-Ser-Arg-AMC | Boc-Phe-Ser-Arg-AMC is a fluorescence peptide substrate with specificity. Boc-Phe-Ser-Arg-AMC can be cleaved by tryptase-like serine proteases (TLSPs) to generate fluorescent products, thereby enabling the detection of TLSPs activity. Boc-Phe-Ser-Arg-AMC can be used in studies related to rosacea. | |||||||||||||||||||||
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References
- [1]. Aki T, et al. Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells. Journal of pharmacological sciences. 2008 Jul;107(3):238-45. [Content Brief]
- [2]. Kanada KN, et al. Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin. The Journal of investigative dermatology. 2012 May;132(5):1435-42.
