2 Results for "

Naratuximab

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Naratuximab" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99374
CAS No.: 1622327-39-2
Synonyms: Anti-TSPAN26/CD37 Reference Antibody (Naratuximab)

Target:  

ADC Antibodies

Research Areas:  

Cancer

Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine .
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Cat. No.: HY-132260
CAS No.: 1607824-64-5
Synonyms: IMGN529; Debio 1562

Research Areas:  

Cancer

Naratuximab emtansine (IMGN529) is a CD37-targeted ADC consisting of a humanized IgG1 mAb coupled to the microtubule disruptor DM1. Naratuximab emtansine has high affinity and specificity for CD37, allowing ADC internalization, processing and intracellular release of DM1. Due to its ability to disrupt microtubule assembly, DM1 can subsequently induce cell cycle arrest and apoptosis .
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