1. Antibody-drug Conjugate/ADC Related
  2. ADC Antibody
  3. Naratuximab

Naratuximab  (Synonyms: Anti-TSPAN26/CD37 Reference Antibody (naratuximab))

Cat. No.: HY-P99374

Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine.

For research use only. We do not sell to patients.

Naratuximab Chemical Structure

Naratuximab Chemical Structure

CAS No. : 1622327-39-2

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Description

Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine[1].

In Vitro

Naratuximab emtansine (IMGN529), an ADC comprised of DM1 linked to a humanized anti-CD37 antibody via the same linker used in Kadcyla. Naratuximab emtansine effectively combines the intrinsic proapoptotic and effector activities of its antibody component with the cytotoxic activity of the maytansinoid payload[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
SMILES

[Naratuximab]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Naratuximab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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