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5 Results for "
OT antagonist-1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "OT antagonist-1" in MCE Product Catalog:
Cat. No.: HY-103650
CAS No.: 479080-38-1
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OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.
Cat. No.: HY-15015
CAS No.: 364071-17-0
Synonyms: Oxytocin receptor antagonist 1
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OT-R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT-R antagonist.
Cat. No.: HY-103651
CAS No.: 2763705-17-3
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OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.
Cat. No.: HY-15016
CAS No.: 364076-99-3
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(E/Z)-OT-R antagonist 1 is a mixture of E/Z forms of OT-R antagonist 1 (HY-15015). OT-R antagonist 1 is a novel, potent, selective non-peptide OT-R antagonist that inhibits oxytocin-induced intracellular Ca 2+ activation (IC50 = 8 nM) .
Cat. No.: HY-15007
CAS No.: 138382-23-7
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L 366509 is a spiroindenylpiperidine camphorsulfonamide oxytocin (OT) antagonist. Modifications led to a new series of o-tolylpiperazine (TP) camphorsulfonamides, exhibiting high affinity for OT receptors and selectivity over arginine vasopressin receptors. Notably, compound 7 (L-368,899) showed excellent OT receptor affinity, potency in inhibiting OT-stimulated uterine contractions, good aqueous solubility, and oral bioavailability in multiple species. Compound 7 has entered clinical testing as an oral and intravenous tocolytic agent. Molecular modeling suggests the TP camphorsulfonamide structure mimics the D-AA2-Ile3 dipeptide, crucial in potent OT antagonists .
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Protocols
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