17 Results for "

PCSK9 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "PCSK9 Antibody" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P9930
CAS No.: 1256937-27-5
Synonyms: AMG 145
Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation .
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1 Cited Publications
Cat. No.: HY-P99187
CAS No.: 1407495-02-6
Synonyms: PF-04950615; RN316

Target:  

PCSK9

Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia .
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1 Cited Publications
Cat. No.: HY-P9928
CAS No.: 1245916-14-6
Synonyms: REGN 727; SAR 236553
Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation .
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1 Cited Publications
Cat. No.: HY-P9928A
CAS No.: 1245916-14-6
Synonyms: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and inflammation .
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Cat. No.: HY-P99626
CAS No.: 1643672-70-1
Synonyms: LY 3015014

Target:  

PCSK9

Research Areas:  

Metabolic Disease

Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9. Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact PCSK9 .
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Cat. No.: HY-P99552
CAS No.: 2225109-03-3
Synonyms: IBI-306

Target:  

PCSK9

Research Areas:  

Cardiovascular Disease

Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia .
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Cat. No.: HY-P991721
CAS No.: 3033317-31-3

Target:  

PCSK9

Research Areas:  

Cardiovascular Disease

Ticalicibart is a humanized IgG4κ monoclonal antibody inhibitor targeting PCSK9. Ticalicibart has anti-hyperlipidaemic activity. Ticalicibart can be used for cardiovascular disease like hypercholesterolaemia research .
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Cat. No.: HY-P990485

Target:  

PCSK9

Research Areas:  

Inflammation/Immunology

Anti-PCSK9 Antibody is a human antibody expressed in CHO, targeting PCSK9. Anti-PCSK9 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-PCSK9 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99773
CAS No.: 2145096-91-7
Synonyms: JS002

Target:  

PCSK9

Ongericimab (JS002) is a humanized anti-PCSK9 monoclonal antibody. Ongericimab has lipid-lowering efficacy. Ongericimab can be used in research of hypercholesteremia and hyperlipidemia .
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Cat. No.: HY-P99871
CAS No.: 2304800-90-4
Synonyms: AK102

Target:  

PCSK9

Research Areas:  

Others

Ebronucimab (AK102) is an IgG1-λ2 antibody targeting PCSK9 and is primarily expressed by CHO DG44 (Chinese Hamster Ovary) cells .
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Cat. No.: HY-P99251
CAS No.: 1355338-54-3
Synonyms: LGT209; NVP-LGT209

Target:  

PCSK9

Research Areas:  

Others

Lodelcizumab is a monoclonal antibody targeting PCSK9. Lodelcizumab can be used for the research of hypercholesterolemia .
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Cat. No.: HY-P991343
Synonyms: ALD309

Target:  

PCSK9

Research Areas:  

Endocrinology

ALD306 is a human monoclonal antibody (mAb) targeting PCSK9. ALD306 can be used in Hypercholesterolaemia research .
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Cat. No.: HY-P990658

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

RG-7652 is a humanized antibody expressed in CHO cells, targeting PCSK9. RG-7652 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.88 kDa. The isotype control for RG-7652 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P992407

Target:  

PCSK9 GLP Receptor

Research Areas:  

Inflammation/Immunology

MEDI-4166 is an antibody-peptide gene fusion molecule of a PCSK9 antibody and a GLP-1 analog. MEDI-4166 is applicable to research related to type 2 diabetes .
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Cat. No.: HY-P81805
Synonyms: HCHOLA3; LDLCQ1; NARC1; Neural apoptosis regulated convertase 1; PC9; PCSK9; Proprotein convertase 9

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P81805A
Synonyms: HCHOLA3; LDLCQ1; NARC1; Neural apoptosis regulated convertase 1; PC9; PCSK9; Proprotein convertase 9

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P85725
Synonyms: Proprotein convertase subtilisin/kexin type 9; Neural apoptosis-regulated convertase 1; NARC-1; Proprotein convertase 9; PC9; Subtilisin/kexin-like protease PC9;

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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