2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Bococizumab

Bococizumab  (Synonyms: PF-04950615; RN316)

Cat. No.: HY-P99187 Purity: 99.9%
COA

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Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia.

For research use only. We do not sell to patients.

Bococizumab Chemical Structure

Bococizumab Chemical Structure

CAS No. : 1407495-02-6

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1 mg USD 420 In-stock
5 mg USD 1050 In-stock
10 mg USD 1680 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Bococizumab Related Antibodies

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Description

Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia[1][2].

IC50 & Target

PCSK9[1]
In Vivo

Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Pregnant Sprague-Dawley (SD) rats[1]
Dosage: 0, 10, 30, and 100 mg/kg
Administration: Intravenous injection (i.v.)
Result: Decreased in fetal cholesterol levels.
Showed well tolerance and no effects on ovarian or uterine parameters.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bococizumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.9%

COA (291 KB)

Handling Instructions (2659 KB)
References
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Bococizumab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bococizumab1407495-02-6PF-04950615 RN316PF04950615PF 04950615RN316RN 316RN-316Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasesHypercholesterolemiacholesterolembryofetalLDL-CInhibitorinhibitorinhibit

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