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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Peptide therapeutics
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Peptide therapeutics" in MCE Product Catalog:
Cat. No.: HY-P10557
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Cat. No.: HY-P11262
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Cat. No.: HY-P11351
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Cat. No.: HY-P5415
CAS No.: 127134-13-8
Cat. No.: HY-N15345
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Cat. No.: HY-187478A
Synonyms: DOPE-PEG2000-Mal-Cys-LIRLWSHLIHIWFQNRRLKWKKK
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DOPE-PEG2000-EB1 (DOPE-PEG2000-Mal-Cys-LIRLWSHLIHIWFQNRRLKWKKK) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the EB1 peptide (a penetratin analog). EB1 peptide is an endosomolytic agent that forms an amphipathic alpha helix upon protonation in endosomes, driving endosomal membrane permeabilization. DOPE-PEG2000-EB1 is used for intracellular delivery of nucleic acids (e.g., siRNA) and other macromolecular therapeutics.
Cat. No.: HY-L110
100 compounds
Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs.
MCE offers a unique collection of 100 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
