2 Results for "

Petasiphenol

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Petasiphenol" in MCE Product Catalog:

Cat. No.: HY-N21777
CAS No.: 145904-50-3
Petasiphenol is a phenolic natural product found in Petasites japonicus, possessing selective inhibitory activity against DNA polymerase λ. Petasiphenol binds to the N-terminal BRCT domain of DNA polymerase λ, with an IC50 of 7.8 μM against DNA polymerase λ . Petasiphenol induces cell growth inhibition, G1 phase cell cycle arrest in human cancer cell lines, and exhibits anti-inflammatory activity against TPA-induced mouse ear inflammation. Petasiphenol can be used for research on cancer and inflammation-related diseases .
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Cat. No.: HY-P3293
CAS No.: 906547-89-5
Synonyms: POL6014
Target:  

Elastase

Research Areas:  

Inflammation/Immunology

Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat (POL6014) has the potential for the research of cystic fibrosis (CF) .
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