2 Results for "

RAS/RAS-RAF-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RAS/RAS-RAF-IN-1" in MCE Product Catalog:

2
RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1
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2 Cited Publications
Cat. No.: HY-138294
CAS No.: 2447039-81-6
Target:  

Ras Raf

Research Areas:  

Cancer

RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μΜ-15 μΜ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity .
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2
Manumycin A
Manumycin A
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2 Cited Publications
Cat. No.: HY-N6796
CAS No.: 52665-74-4
Category:  

Infection Microorganisms Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics

Target:  

Antibiotic Exosomes Farnesyl Transferase Ras Apoptosis Phospholipase TNF Receptor Atg8/LC3

Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion .
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