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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
Rat-1
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "Rat-1" in MCE Product Catalog:
7
7 Publications Verification
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E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat .
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4 Cited Publications
Cat. No.: HY-N0361
CAS No.: 19408-84-5
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1 Cited Publications
Cat. No.: HY-N6020B
CAS No.: 21913-99-5
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Cardiovascular Disease Dalbergia odorifera T. Chen Flavonoids Leguminosae Flavonones Phenols Polyphenols Plants Disease Research Fields
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PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy [1].
Cat. No.: HY-W010144
CAS No.: 92-43-3
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Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat . Phenidone is used as a photographic developer .
Cat. No.: HY-NP019
Cat. No.: HY-164704
CAS No.: 277333-45-6
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JA2 is an inhibitor of metalloendopeptidase 24.15 that can potentiate the hypotensive response to bradykinin in rat .
Cat. No.: HY-P3219
CAS No.: 10551-48-1
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GSK737 is a BRD4 BD1 and BD2 inhibitor, with pIC50 values of 5.3 and 7.3 respectively. GSK737 has low clearance and good solubility and permeability in rat .
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Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm . Xanthopterin (XPT) causes renal growth and hypertrophy in rat .
Xanthopterin inhibits RNA synthesis .
Cat. No.: HY-P3684A
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Cat. No.: HY-171130
Cy3 MicroRNA Antagomir Negative Control is a Cy3-labeled MicroRNA Antagomir Negative Control (HY-RI04602A). The sequence of MicroRNA Antagomir Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat .
Cat. No.: HY-117962A
CAS No.: 2740807-77-4
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BI 703704 is a potent soluble guanylate cyclase (sGC) activator. BI 703704 inhibits the progression of diabetic nephropathy in the ZSF1 rat .
Cat. No.: HY-P3984
CAS No.: 129813-57-6
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Norbormide, a rodenticide, is a calcium entry blocker with a selective vasoconstrictor activity. Norbormide shows species- and tissue-specific, endothelium independent, and is restricted to the peripheral arteries of rat .
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HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 μM and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO does not inhibits mGlu2 and mGlu4a. HexylHIBO decreased spontaneous excitatory postsynaptic currents (sEPSCs) in rat .
Cat. No.: HY-119674AR
CAS No.: 5979-01-1
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Cat. No.: HY-N0361R
CAS No.: 19408-84-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
