2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. HexylHIBO

HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO decreased sEPSC in rat.

For research use only. We do not sell to patients.

HexylHIBO Chemical Structure

HexylHIBO Chemical Structure

CAS No. : 334887-43-3

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Based on 1 publication(s) in Google Scholar

HexylHIBO Related Antibodies

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Description

HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO decreased sEPSC in rat[1].

In Vitro

Thus ambient levels of glutamate tonically activate mGluRs and regulate cortical excitability[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HexylHIBO Related Antibodies
Molecular Weight

256.30

Formula

C12H20N2O4
CAS No.
SMILES

O=C(O)C(N)CC(ON1)=C(CCCCCC)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HexylHIBO Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HexylHIBO334887-43-3mGluRMetabotropic glutamate receptorssEPSCgroupIglutamateInhibitorinhibitorinhibit

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