334887-43-3
334887-43-3
Chemical Structure
HexylHIBO
- CAS No.: 334887-43-3
- Formula:C12H20N2O4
- Molecular Weight:256.30
IUPAC Name: 2-amino-3-(4-hexyl-3-oxo-2,3-dihydroisoxazol-5-yl)propanoic acid
InChIKey: OKJBLHIYOWSQDJ-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CC(ON1)=C(CCCCCC)C1=O
Biological Activity: HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 μM and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO does not inhibits mGlu2 and mGlu4a. HexylHIBO decreased spontaneous excitatory postsynaptic currents (sEPSCs) in rat[1].
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HexylHIBO | 98.0% | HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 μM and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO does not inhibits mGlu2 and mGlu4a. HexylHIBO decreased spontaneous excitatory postsynaptic currents (sEPSCs) in rat. | ||||||||||||||||||||
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References
Keywords
