92-43-3
92-43-3
Chemical Structure
Phenidone
- CAS No.: 92-43-3
- Formula:C9H10N2O
- Molecular Weight:162.19
IUPAC Name: 1-phenylpyrazolidin-3-one
InChIKey: CMCWWLVWPDLCRM-UHFFFAOYSA-N
SMILES: O=C1NN(C2=CC=CC=C2)CC1
Biological Activity: Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Phenidone | 98.96% | Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Phenidone is used as a photographic developer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Phenidone (Standard) | ≥98% | Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Phenidone is used as a photographic developer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.83
HY-W1034631-Phenyl-2-pyrrolidinone -
Similarity Score 0.76
HY-B0099Edaravone -
Similarity Score 0.72
HY-78240RPhenylpiperazine (Standard) -
Similarity Score 0.70
HY-Y0788Indoline -
Similarity Score 0.70
HY-W0021083,4-Dihydroquinolin-2(1H)-one -
Similarity Score 0.70
HY-W012179Phenylpiperazine hydrochloride -
Similarity Score 0.67
HY-121641Nitrosobenzene -
Similarity Score 0.67
HY-150799CRBN ligand-1 -
Similarity Score 0.67
HY-W017425N'-Phenylacetohydrazide -
Explore the MedChemAI to find more analogs
References
- [1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210. [Content Brief]
- [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58. [Content Brief]
- [3]. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587. [Content Brief]
