6 Results for "

Renal protective agent

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Renal protective agent" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N2263
CAS No.: 93-39-0
Synonyms: Umbelliferone glucoside
Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin can improve creatinine clearance, and reduce plasma creatinine, and kidney injuries. Skimmin has good anti-amoebic activity against the HM1:IMMS strain of Entamoeba histolytica. Skimmin has anti-cancer and neuroprotective activities. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues. Skimmin can be studied in research for diabetes and diabetes-related diseases .
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Cat. No.: HY-B1016
CAS No.: 15421-84-8
Synonyms: AR-12008
Trapidil (AR-12008) is an orally active vasodilator and antiplatelet agent. Trapidil antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production. Trapidil promotes prostacyclin biosynthesis, reduces lipid peroxidation, regulates nitric oxide metabolism, and inhibits cell proliferation and migration. Trapidil exerts tissue-protective effects, regulates bone turnover, and inhibits pyroptosis via the GPX3/Nrf2 pathway. Trapidil is applicable to research related to renal ischemia-reperfusion injury, chronic stable angina, restenosis, meningioma, diabetic cardiomyopathy and peripheral nerve crush injury .
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Cat. No.: HY-114683
CAS No.: 105955-01-9
Purity:  99.71%
Target:  

TGF-beta/Smad

Research Areas:  

Cardiovascular Disease

KS370G is an orally active hypoglycemic and cardiovascular protective agent. KS370G improves left ventricular hypertrophy and function in pressure-overload mice heart. KS370G reduces renal obstructive nephropathy .
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Cat. No.: HY-116794
CAS No.: 34634-22-5
Purity:  99.83%
Synonyms: 2,2-Diphenylethyl isothiocyanate
Research Areas:  

Cancer

SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease .
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Cat. No.: HY-B1016R
CAS No.: 15421-84-8
Synonyms: AR-12008 (Standard)
Trapidil (Standard) (AR-12008 (Standard)) is the analytical standard of Trapidil (HY-B1016R). This product is intended for research and analytical applications. Trapidil (AR-12008) is an orally active vasodilator and antiplatelet agent. Trapidil antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production. Trapidil promotes prostacyclin biosynthesis, reduces lipid peroxidation, regulates nitric oxide metabolism, and inhibits cell proliferation and migration. Trapidil exerts tissue-protective effects, regulates bone turnover, and inhibits pyroptosis via the GPX3/Nrf2 pathway. Trapidil is applicable to research related to renal ischemia-reperfusion injury, chronic stable angina, restenosis, meningioma, diabetic cardiomyopathy and peripheral nerve crush injury.
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Cat. No.: HY-N20390
Scrophularia ningpoensis extract is an orally effective hypoglycemic and antioxidant agent. Scrophularia ningpoensis extract reduces fasting blood glucose levels, increases plasma insulin levels, ameliorates impaired antioxidant status, scavenges free radicals, inhibits lipid peroxidation, and decreases elevated serum creatinine and serum urea levels. Scrophularia ningpoensis extract reduces the risk of developing diabetic complications. Scrophularia ningpoensis extract is applicable to diabetes-related research .
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