105955-01-9
105955-01-9
Chemical Structure
KS370G
- CAS No.: 105955-01-9
- Formula:C17H17NO3
- Molecular Weight:283.32
IUPAC Name: (E)-3-(3,4-dihydroxyphenyl)-N-phenethylacrylamide
InChIKey: QOWABIXYAFJMQE-VQHVLOKHSA-N
SMILES: O=C(/C=C/C1=CC=C(C(O)=C1)O)NCCC2=CC=CC=C2
Biological Activity: KS370G is an orally active hypoglycemic and cardiovascular protective agent. KS370G improves left ventricular hypertrophy and function in pressure-overload mice heart. KS370G reduces renal obstructive nephropathy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
KS370G | 99.44% | KS370G is an orally active hypoglycemic and cardiovascular protective agent. KS370G improves left ventricular hypertrophy and function in pressure-overload mice heart. KS370G reduces renal obstructive nephropathy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.87
HY-N8241RN-trans-Caffeoyltyramine (Standard) -
Similarity Score 0.84
HY-N7203RN-Caffeoyl O-methyltyramine (Standard) -
Similarity Score 0.83
HY-W127945N-(E)-Caffeoyldopamine -
Similarity Score 0.83
HY-N0274Caffeic acid phenethyl ester -
Similarity Score 0.83
HY-W1058007(E)-Caffeic acid phenethyl ester -
Similarity Score 0.82
HY-N17646N-trans-Cinnamoyltyramine -
Similarity Score 0.80
HY-170839TRPV1-IN-3 -
Similarity Score 0.80
HY-N2230A(E/Z)-N-p-trans-Coumaroyltyramine -
Similarity Score 0.80
HY-N2230RN-p-trans-Coumaroyltyramine (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Chuang ST, et al. KS370G, a caffeamide derivative, attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice. Eur J Pharmacol. 2015 Mar 5;750:1-7. [Content Brief]
- [2]. Weng YC, et al. KS370G, a synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart. Eur J Pharmacol. 2012 Jun 5;684(1-3):108-15. [Content Brief]
