2. Apoptosis MAPK/ERK Pathway
  3. Apoptosis JNK MDM-2/p53 Caspase
  4. SF5

SF5  (Synonyms: 2,2-Diphenylethyl isothiocyanate)

Cat. No.: HY-116794 Purity: 99.83%
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SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease.

For research use only. We do not sell to patients.

SF5 Chemical Structure

SF5 Chemical Structure

CAS No. : 34634-22-5

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10 mg USD 70 In-stock
25 mg USD 120 In-stock
50 mg USD 175 In-stock
100 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

SF5 Related Antibodies

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Description

SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease[1].

Molecular Weight

239.34

Formula

C15H13NS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C=NCC(C1=CC=CC=C1)C2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (522.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1782 mL 20.8908 mL 41.7816 mL
5 mM 0.8356 mL 4.1782 mL 8.3563 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1782 mL 20.8908 mL 41.7816 mL 104.4539 mL
5 mM 0.8356 mL 4.1782 mL 8.3563 mL 20.8908 mL
10 mM 0.4178 mL 2.0891 mL 4.1782 mL 10.4454 mL
15 mM 0.2785 mL 1.3927 mL 2.7854 mL 6.9636 mL
20 mM 0.2089 mL 1.0445 mL 2.0891 mL 5.2227 mL
25 mM 0.1671 mL 0.8356 mL 1.6713 mL 4.1782 mL
30 mM 0.1393 mL 0.6964 mL 1.3927 mL 3.4818 mL
40 mM 0.1045 mL 0.5223 mL 1.0445 mL 2.6113 mL
50 mM 0.0836 mL 0.4178 mL 0.8356 mL 2.0891 mL
60 mM 0.0696 mL 0.3482 mL 0.6964 mL 1.7409 mL
80 mM 0.0522 mL 0.2611 mL 0.5223 mL 1.3057 mL
100 mM 0.0418 mL 0.2089 mL 0.4178 mL 1.0445 mL
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SF5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SF534634-22-52,2-Diphenylethyl isothiocyanateSF 5SF-5ApoptosisJNKMDM-2/p53Caspasec-Jun N-terminal kinaseSulforaphane analogue LLC-PK1Renal protective agentInhibitorinhibitorinhibit

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