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19 Results for "
Ribociclib
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Ribociclib" in MCE Product Catalog:
84
84 Publications Verification
Synonyms: LEE011
Target:
Research Areas:
RRibociclib (LEE011) is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
84
84 Publications Verification
Synonyms: LEE011 hydrochloride
Target:
Research Areas:
RRibociclib (LEE011) hydrochloride is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
84
84 Publications Verification
Synonyms: LEE011 succinate
Target:
Research Areas:
RRibociclib (LEE011) succinate is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
84
84 Publications Verification
Synonyms: LEE011 succinate hydrate
RRibociclib (LEE011) succinate hydrate is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
Cat. No.: HY-15777S
CAS No.: 1328934-40-2
Synonyms: LEE011-d6
BSJ-04-132 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC), with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity .
Cat. No.: HY-15777R
CAS No.: 1211441-98-3
Synonyms: LEE011 (Standard)
Target:
Research Areas:
Ribociclib (Standard) is the analytical standard of Ribociclib. This product is intended for research and analytical applications. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
Synonyms: LEE011-d6 hydrochloride
Cat. No.: HY-171459
CAS No.: 1211441-59-6
Synonyms: N-Desmethyl Ribociclib
Target:
Research Areas:
LEQ803 (N-Desmethyl Ribociclib) is a drug metabolite of the CDK4/6 inhibitor Ribociclib (HY-15777), which is produced through metabolism by CYP3A4. LEQ803 has potential application value in the field of oncology .
Cat. No.: HY-15777AR
CAS No.: 1211443-80-9
Synonyms: LEE011 hydrochloride (Standard)
Target:
Research Areas:
Ribociclib (Standard) (LEE011(Standard)) hydrochloride is the analytical standard of Ribociclib hydrochloride (HY-15777A). This product is intended for research and analytical applications. Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
Synonyms: LEE011-d8
Cat. No.: HY-78750
CAS No.: 1211443-61-6
Target:
Research Areas:
Ribociclib impurity 1 is an impurity of Ribociclib.
Cat. No.: HY-15777BR
CAS No.: 1374639-75-4
Synonyms: LEE011 succinate (Standard)
Target:
Research Areas:
Ribociclib succinate (Standard) is the analytical standard of Ribociclib succinate. This product is intended for research and analytical applications. Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
Cat. No.: HY-164949
CAS No.: 2762182-61-4
Target:
Research Areas:
Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic .
Cat. No.: HY-42543
CAS No.: 1082876-26-3
Synonyms: Ribociclib impurity C
Target:
Research Areas:
Ribociclib impurity 3 (Ribociclib impurity C) is an impurity of Ribociclib.
Cat. No.: HY-78751
CAS No.: 1374639-78-7
Synonyms: Ribociclib impurity B
Target:
Research Areas:
Ribociclib impurity 2 (Ribociclib impurity B) is an impurity of Ribociclib.
Cat. No.: HY-32206
CAS No.: 775288-71-6
Synonyms: OTAVA-BB 1314167
Target:
Research Areas:
Ribociclib impurity 5 (OTAVA-BB 1314167) is an impurity of Ribociclib.
Cat. No.: HY-171459S
CAS No.: 1328934-43-5
Synonyms: N-Desmethyl Ribociclib-d3
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
