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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
S-101
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "S-101" in MCE Product Catalog:
Cat. No.: HY-165526
CAS No.: 362508-67-6
Research Areas:
S101 is an inhibitor of SLP-76 and AhR. By inhibiting SLP-76 phosphorylation, S101 blocks the TCR signaling pathway and prevents AhR nuclear translocation, thereby selectively suppressing the proliferation of activated T cells, inducing their apoptosis, and reducing TNF-α levels. S101 can be used in studies of graft rejection, psoriasis, and superantigen-induced toxic shock .
5
5 Cited Publications
Synonyms: EDO-S101; NL-101
Tinostamustine (EDO-S101) is a pan HDAC inhibitor; inhibits HDAC6, HDAC1, HDAC2 and HDAC3 with IC50 values of 6 nM, 9 nM, 9 nM and 25 nM, respectively .
1
1 Cited Publications
Cat. No.: HY-P7873
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRYAB; Heat-Shock 20 KD Like-Protein; Prev. CRYA2; HEL-S-101; HSPB5; CTRCT16; Alpha-Crystallin B Chain; CMD1II; Heat Shock Protein Family B Member 5; CTPP2; Renal Carcinoma Antigen NY-REN-27; MFM2A; Heat Shock Protein Beta-5; MFM2B; Rosenthal Fiber Component; HspB5; Alpha(B)-Crystallin; MFM2; Epididymis Secretory Protein Li 101; Crystallin Alpha B; Crystallin, Alpha B
Species:
Human
Source:
E. coli
Cat. No.: HY-B1937
CAS No.: 25155-30-0
Synonyms: Bio-Soft S 101 sodium
Cat. No.: HY-B1937R
CAS No.: 25155-30-0
Synonyms: Bio-Soft S 101 sodium (Standard)
Cat. No.: HY-101780A
CAS No.: 1793059-58-1
Synonyms: EDO-S101 hydrochloride; NL-101 hydrochloride
Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice .
Cat. No.: HY-181876
CAS No.: 3124701-00-1
Target:
Research Areas:
F44-S101 is an orally active, potent, and selective gut-restricted FXR antagonist with an IC50 of 0.48 μM and lipid-lowering activity. F44-S101 selectively antagonizes intestinal FXR, feedback-activates hepatic FXR, promotes cholesterol metabolism and reduces lipid accumulation. F44-S101 decreases total cholesterol, triglyceride and low-density lipoprotein cholesterol levels. F44-S101 can be used in studies related to hyperlipidemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
