1236199-60-2
1236199-60-2
Chemical Structure
Tinostamustine
Synonym(s): EDO-S101; NL-101
- CAS No.: 1236199-60-2
- Formula:C19H28Cl2N4O2
- Molecular Weight:415.36
IUPAC Name: 7-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)-N-hydroxyheptanamide
InChIKey: GISXTRIGVCKQBX-UHFFFAOYSA-N
SMILES: O=C(NO)CCCCCCC1=NC2=CC(N(CCCl)CCCl)=CC=C2N1C
Biological Activity: Tinostamustine (EDO-S101) is a pan HDAC inhibitor; inhibits HDAC6, HDAC1, HDAC2 and HDAC3 with IC50 values of 6 nM, 9 nM, 9 nM and 25 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tinostamustine | 99.64% | Tinostamustine (EDO-S101) is a pan HDAC inhibitor; inhibits HDAC6, HDAC1, HDAC2 and HDAC3 with IC50 values of 6 nM, 9 nM, 9 nM and 25 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-101780ATinostamustine hydrochloride -
Similarity Score 0.81
HY-B0077Bendamustine hydrochloride -
Similarity Score 0.81
HY-13567RBendamustine (Standard) -
Similarity Score 0.80
HY-13567ABendamustine hydrochloride hydrate -
Similarity Score 0.72
HY-117909CEP-40125 -
Similarity Score 0.68
HY-134051RBendamustine dihydroxy ester (Standard) -
Similarity Score 0.62
HY-137200N-Desmethyl Bendamustine -
Similarity Score 0.62
HY-13567SBendamustine-d4 -
Similarity Score 0.56
HY-B0077S1Bendamustine-d8 hydrochloride -
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