2 Results for "

SOS1 catalytic activity inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SOS1 catalytic activity inhibitor" in MCE Product Catalog:

Cat. No.: HY-124514
CAS No.: 487001-04-7
Target:  

SOS1 Ras ERK

Research Areas:  

Cancer

UC-857993 is a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), suppressing catalytic activity. UC-857993 also inhibits ERK and Ras activation, suppresses the growth of mouse embryonic fibroblasts (MEFs) .
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Cat. No.: HY-122685
CAS No.: 116679-70-0
Target:  

SOS1

Research Areas:  

Cancer

UC-773587 is a selective SOS1 catalytic activity inhibitor. UC-773587 binds to the catalytic site of Sos1 over HRas and ITSN (a RhoGEF) and inhibits nucleotide exchange with an IC50 value of 4.5 μM. UC-773587 mappes to the Ras switch II interaction region of the Sos1 catalytic site. UC-773587 can be used for the study of prostate cancer .
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