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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
SUCNR1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "SUCNR1" in MCE Product Catalog:
14
14 Publications Verification
Target:
Research Areas:
NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM [1].
14
14 Publications Verification
Cat. No.: HY-130246A
CAS No.: 2728500-80-7
Target:
Research Areas:
NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM [1].
4
4 Cited Publications
Cat. No.: HY-N1910
CAS No.: 20784-60-5
3
3 Cited Publications
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Research Areas:
cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system [1].
1
1 Cited Publications
Cat. No.: HY-RS14004
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Research Areas:
Sucnr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sucnr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Research Areas:
SUCNR1-IN-1 is an orally active SUCNR1 inhibitor. SUCNR1-IN-1 exhibits inhibitory rates of 23% and 56% against rat and mouse SUCNR1 at 100 μM, respectively. SUCNR1-IN-1 can be used in the research of rheumatoid arthritis [1].
Target:
Research Areas:
Succinate/succinate receptor antagonist 1 is an antagonist of the succinate/succinate receptor. Succinate/succinate receptor antagonist 1 can inhibit the activation of succinate receptor 1 (SUCNR1). Succinate/succinate receptor antagonist 1 can block succinate signaling. Succinate/succinate receptor antagonist 1 can be used for the study of periodontal disease [1].
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Research Areas:
SUCNR1-IN-2 (Statement 35) is a SUCNR1 inhibitor. SUCNR1-IN-2 can be used for the study of neurodegenerative diseases such as neuroinflammation [1].
Cat. No.: HY-RS14003
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Research Areas:
SUCNR1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUCNR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14005
Target:
Research Areas:
Sucnr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sucnr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183639
Target:
Research Areas:
SUCNR1 antagonist-1 is an orally active SUCNR1 antagonist. SUCNR1 antagonist-1 forms stable, water-bridged hydrogen bonds with key residue Glu22 1.31 to stabilize binding conformation and modulates protein conformational flexibility. SUCNR1 antagonist-1 blocks succinate-mediated SUCNR1 signaling and induces cell apoptosis. SUCNR1 antagonist-1 can be used for the research of colorectal carcinoma [1].
Cat. No.: HY-P705683
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SUCNR1; G Protein-Coupled Receptor 91; Prev. GPR91; P2Y Purinoceptor 1; G-Protein Coupled Receptor 91; Succinate Receptor 1; P2Y Purinoceptor 1-Like
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
