2380230-73-7
2380230-73-7
Chemical Structure
NF-56-EJ40
- CAS No.: 2380230-73-7
- Formula:C27H29N3O3
- Molecular Weight:443.54
IUPAC Name: 2-(2-(4'-((4-methylpiperazin-1-yl)methyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)acetic acid
InChIKey: UTWXDNZWMQAUKL-UHFFFAOYSA-N
SMILES: O=C(NC1=C(CC(O)=O)C=CC=C1)C2=CC=CC(C3=CC=C(CN4CCN(C)CC4)C=C3)=C2
Biological Activity: NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NF-56-EJ40 | 99.88% | NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM. | ||||||||||||||||||||
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References
Keywords
