3 Results for "

SYN1327

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "SYN1327" in MCE Product Catalog:

Cat. No.: HY-P11786
CAS No.: 1020264-43-0
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 can be used in studies related to IgG-mediated autoimmune diseases .
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Cat. No.: HY-P11786A
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 acetate is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 acetate competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acetate acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 acetate can be used in studies related to IgG-mediated autoimmune diseases .
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Cat. No.: HY-145775
CAS No.: 1425051-22-4
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

hIgG-hFc receptor-IN-1 is a quinoxaline-based human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor with an IC50 of 2 μM. hIgG-hFc receptor-IN-1 blocks the binding of hIgG to human FcRn. hIgG-hFc receptor-IN-1 can be used for immune-related research .
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