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Scutellarein

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By Targets:	Autophagy (2) Bacterial (2) Cholinesterase (ChE) (1) COX (2) CXCR (1) Isotope-Labeled Compounds (1) Molecular Glues (1) NF-κB (2) NO Synthase (2) Reference Standards (2) SARS-CoV (2) Src (2)
By Research Areas:	Cancer (5) Infection (2) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (3)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0752

*Scutellarein* 10+ Cited Publications 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone	Src Autophagy SARS-CoV	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

HY-N4314

Scutellarein tetramethyl ether 4 Publications Verification 4',5,6,7-Tetramethoxyflavone	Bacterial COX NO Synthase NF-κB	Infection Inflammation/Immunology Cancer
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-N9925

Plantaginin Scutellarein-7-O-glucoside	Others	Others
Plantaginin is a glycoside can be isolated from fresh leaves of Plantago asiatica L. .

HY-N0752R

Scutellarein (Standard) 6-Hydroxyapigenin (Standard); 4',5,6,7-Tetrahydroxyflavone (Standard)	Reference Standards Src Autophagy SARS-CoV	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Scutellarein (Standard) is the analytical standard of Scutellarein. This product is intended for research and analytical applications. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

HY-179035

TBS6b	Molecular Glues CXCR	Cancer
TBS6b is a potent and selective ACKR3 molecular glue degrader. TBS6b degrades ACKR3 via the ubiquitin-proteasome pathway. TBS6b inhibits hepatocellular carcinoma cell proliferation, migration, and invasion. TBS6b is relevant to hepatocellular carcinoma (HCC) research .

HY-N4314R

Scutellarein tetramethyl ether (Standard) 4',5,6,7-Tetramethoxyflavone (Standard)	Reference Standards Bacterial COX NO Synthase NF-κB	Infection Inflammation/Immunology Cancer
Scutellarein tetramethyl ether (Standard) is the analytical standard of Scutellarein tetramethyl ether. This product is intended for research and analytical applications. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-W754220

Scutellarein-d6 6-Hydroxyapigenin-d₆; 4',5,6,7-Tetrahydroxyflavone-d₆	Isotope-Labeled Compounds	Others
Scutellarein-d₆ (6-Hydroxyapigenin-d₆) is deuterium labeled Scutellarein .

HY-N17775

Scutellarein 4'-methyl ether 7-O-glucuronide Clerodendroside	Cholinesterase (ChE)	Neurological Disease
Scutellarein 4'-methyl ether 7-O-glucuronide (Clerodendroside) is a flavonoid inhibitor of acetylcholinesterase (AChE) (IC₅₀=1 mg/mL). Scutellarein 4'-methyl ether 7-O-glucuronide can be isolated from Plectranthus barbatus. It also possesses antioxidant activity and can be used in research on neurological diseases such as Alzheimer's disease.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0752

*Scutellarein* 10+ Cited Publications 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone	Flavonoids Classification of Application Fields Flavones Labiatae Phenols Polyphenols Plants Medicago truncatula Gaertn. Disease Research Fields Source Classification Cancer	Src Autophagy SARS-CoV
Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

HY-N4314

Scutellarein tetramethyl ether 4 Publications Verification 4',5,6,7-Tetramethoxyflavone	Infection Flavonoids Classification of Application Fields Flavones Plants Compositae Genista maderensis (Webb & Berthel.) Lowe Inflammation/Immunology Disease Research Fields	Bacterial COX NO Synthase NF-κB
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-N9925

Plantaginin Scutellarein-7-O-glucoside	Plantaginaceae Monophenols Phenols Plantago asiatica L. Plants Source Classification	Others
Plantaginin is a glycoside can be isolated from fresh leaves of Plantago asiatica L. .

HY-N0752R

Scutellarein (Standard) 6-Hydroxyapigenin (Standard); 4',5,6,7-Tetrahydroxyflavone (Standard)	Structural Classification Flavonoids Flavones Labiatae Phenols Polyphenols Plants Medicago truncatula Gaertn. Source Classification	Reference Standards Src Autophagy SARS-CoV
Scutellarein (Standard) is the analytical standard of Scutellarein. This product is intended for research and analytical applications. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

HY-N4314R

Scutellarein tetramethyl ether (Standard) 4',5,6,7-Tetramethoxyflavone (Standard)	Structural Classification Flavonoids Flavones Plants Compositae Genista maderensis (Webb & Berthel.) Lowe	Reference Standards Bacterial COX NO Synthase NF-κB
Scutellarein tetramethyl ether (Standard) is the analytical standard of Scutellarein tetramethyl ether. This product is intended for research and analytical applications. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

HY-N17775

Scutellarein 4'-methyl ether 7-O-glucuronide Clerodendroside	Structural Classification Flavonoids Flavones Labiatae Plants Pueraria montana (Lour.) Merr. Source Classification	Cholinesterase (ChE)
Scutellarein 4'-methyl ether 7-O-glucuronide (Clerodendroside) is a flavonoid inhibitor of acetylcholinesterase (AChE) (IC₅₀=1 mg/mL). Scutellarein 4'-methyl ether 7-O-glucuronide can be isolated from Plectranthus barbatus. It also possesses antioxidant activity and can be used in research on neurological diseases such as Alzheimer's disease.

Cat. No.	Product Name	Chemical Structure

HY-W754220

Scutellarein-d6
Scutellarein-d₆ (6-Hydroxyapigenin-d₆) is deuterium labeled Scutellarein .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Scutellarein

Inhibitors & Agonists

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Isotope-Labeled Compounds

Natural
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