3 Results for "

T-acute lymphoblastic leukemia

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "T-acute lymphoblastic leukemia" in MCE Product Catalog:

Cat. No.: HY-120372
CAS No.: 1584631-89-9
Target:  

Notch

Research Areas:  

Cancer

BMS-871 is an orally active pan-Notch inhibitor with IC50 values ​​of 4/1/4/3 nM for Notch1/2/3/4, respectively. BMS-871 significantly inhibited the proliferation of TALL-1 and MDA-MB-157 cells and demonstrated significant antitumor activity in T-acute lymphoblastic leukemia and triple-negative breast cancer xenograft models. BMS-871 can be used to study leukemia and breast cancer .
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Cat. No.: HY-155188
CAS No.: 2290611-26-4
Target:  

Bcl-2 Family

Research Areas:  

Neurological Disease

NWP-0476 is BCL-2/BCL-xL inhibitor. NWP-0476 has a modified structure with fine-tuned BCL-xL activity. NWP-0476 can be used for relapsed T-acute lymphoblastic leukemia (T-ALL) research .
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Cat. No.: HY-P991328

Target:  

Notch

Research Areas:  

Cancer

MAb604.107 is a human monoclonal antibody (mAb) targeting NOTCH1. MAb604.107 inhibits the proliferation and CD34/CD44 expression of primary T-ALL cells. MAb604.107 has anti-tumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. MAb604.107 can be used in T acute lymphoblastic leukemia research .
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