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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

TGFb1 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	TGF-beta/Smad (4) TGF-β Receptor (3)
By Research Areas:	Cancer (2) Inflammation/Immunology (4) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99305

Metelimumab 3 Publications Verification CAT-192; Anti-TGFb1 Recombinant Antibody	TGF-β Receptor	Inflammation/Immunology
Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1 .

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells .

HY-P990517

**Anti-TGFb1 Antibody**	TGF-beta/Smad	Inflammation/Immunology
Anti-TGFb1 Antibody is a humanized antibody expressed in CHO cells that targets *TGFb1. The Anti-TGFb1* Antibody has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TGFb1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99606

Cirevetmab ZTS-00521426	TGF-beta/Smad	Inflammation/Immunology
Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris *TGFB1* caninized monoclonal antibody. Cirevetmab is an immunomodulator .

HY-P991382

SAR-439459	TGF-β Receptor	Cancer
SAR-439459 is a human monoclonal antibody (mAb) targeting TGFB1/TGFβ-1. SAR-439459 blocks TGFβ-mediated pSMAD signaling, and suppression of T cells and NK cells. SAR-439459 has anti-tumor activity .

HY-P991383

LY2382770	TGF-β Receptor	Metabolic Disease
LY2382770 is a human monoclonal antibody (mAb) targeting *TGFB1*. LY2382770 can be used in dabetic nephropathies research .

HY-P991950

SHR-1906	TGF-beta/Smad	Inflammation/Immunology
SHR-1906 is a selective fully humanized monoclonal IgG1 inhibitory antibody targeting CTGF. SHR-1906 specifically binds to CTGF, thereby blocking the interaction between CTGF and *TGF-B1* with an inhibition rate of 55%. SHR-1906increases the survival rate in a pulmonary fibrosis model by reducing TGF-β1 levels and inhibiting fibrotic lesions in lung tissue in Bleomycin (HY-108345)-induced pulmonary fibrosis.SHR-1906 can be used for pulmonary fibrosis (IPF) research. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99305

Metelimumab 3 Publications Verification CAT-192; Anti-TGFb1 Recombinant Antibody	TGF-β Receptor	Inflammation/Immunology
Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1 .

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells .

HY-P990517

**Anti-TGFb1 Antibody**	TGF-beta/Smad	Inflammation/Immunology
Anti-TGFb1 Antibody is a humanized antibody expressed in CHO cells that targets *TGFb1. The Anti-TGFb1* Antibody has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TGFb1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99606

Cirevetmab ZTS-00521426	TGF-beta/Smad	Inflammation/Immunology
Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris *TGFB1* caninized monoclonal antibody. Cirevetmab is an immunomodulator .

HY-P991382

SAR-439459	TGF-β Receptor	Cancer
SAR-439459 is a human monoclonal antibody (mAb) targeting TGFB1/TGFβ-1. SAR-439459 blocks TGFβ-mediated pSMAD signaling, and suppression of T cells and NK cells. SAR-439459 has anti-tumor activity .

HY-P991383

LY2382770	TGF-β Receptor	Metabolic Disease
LY2382770 is a human monoclonal antibody (mAb) targeting *TGFB1*. LY2382770 can be used in dabetic nephropathies research .

HY-P991950

SHR-1906	TGF-beta/Smad	Inflammation/Immunology
SHR-1906 is a selective fully humanized monoclonal IgG1 inhibitory antibody targeting CTGF. SHR-1906 specifically binds to CTGF, thereby blocking the interaction between CTGF and *TGF-B1* with an inhibition rate of 55%. SHR-1906increases the survival rate in a pulmonary fibrosis model by reducing TGF-β1 levels and inhibiting fibrotic lesions in lung tissue in Bleomycin (HY-108345)-induced pulmonary fibrosis.SHR-1906 can be used for pulmonary fibrosis (IPF) research. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

Host:	Mouse (4)
Reactivity:	Human (2) Mouse (4) Rat (4)
Application:	IHC-P (4) IF-Tissue (2) IHC-F (2) FC (2)
Isotype:	IgG1 (2) IgG2a (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86743

	TGF beta 1 Antibody (YA6435) CED; DPD1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFb; TGFb-1; TGFb1; TGFb1_HUMAN; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor, beta 1.	IHC-P, IHC-F, IF-Tissue	Rat, Mouse
	TGF beta 1 Antibody (YA6435) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TGF beta 1.

HY-P86743A

	TGF beta 1 Antibody (YA6435)(PBS only) CED; DPD1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFb; TGFb-1; TGFb1; TGFb1_HUMAN; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor, beta 1.	IHC-P, IHC-F, IF-Tissue	Rat, Mouse
	TGF beta 1 Antibody (YA6435) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TGF beta 1.

HY-P88874

	TSC22D1 Antibody (YA8558) Ptg-2; TGFb1I4; TSC22	IHC-P, FC	Human, Mouse, Rat
	TSC22D1 Antibody (YA8558) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TSC22D1.

HY-P88874A

	TSC22D1 Antibody (YA8558)(PBS only) Ptg-2; TGFb1I4; TSC22	IHC-P, FC	Human, Mouse, Rat
	TSC22D1 Antibody (YA8558) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TSC22D1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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