16 Results for "

TLR2 protein

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "TLR2 protein" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P73591
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TLR2; CD282; Toll Like Receptor 2; Toll/Interleukin-1 Receptor-Like protein 4; Toll-Like Receptor 2; Toll-Like Receptor; TIL4; CD282 Antigen
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P73590
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TLR2; CD282; Toll Like Receptor 2; Toll/Interleukin-1 Receptor-Like protein 4; Toll-Like Receptor 2; Toll-Like Receptor; TIL4; CD282 Antigen
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P81134
Synonyms: Toll-like receptor 2; Toll like receptor 2; Toll like receptor 2 precursor; Toll-like receptor 2; TLR 2; TLR-2; Toll/interleukin-1 receptor-like protein 4; CD282 antigen; CD282; TIL 4; TIL4; TLR2_HUMAN; Toll/interleukin 1 receptor like 4; Toll/interleukin 1 receptor like protein 4; Toll/interleukin receptor like protein 4.

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-159069
CAS No.: 9010-72-4
Purity:  95.02%
Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .
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Cat. No.: HY-N2055
CAS No.: 19895-95-5
Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .
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Cat. No.: HY-142980
CAS No.: 62700-69-0
Synonyms: Dioleoylphosphatidylglycerol
DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .
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Cat. No.: HY-173309
P53/TLR2 modulator-1 (Compound Z9) is a modulator that targets both the P53 pathway and TLR2 simultaneously, exhibiting anti-radiation activity. P53/TLR2 modulator-1 reduces apoptosis by inhibiting the radiation-induced expression of P53 and Bax. At the same time, it activates the TLR2 pathway, upregulates the expression of downstream proteins MyD88 and P65, and promotes the secretion of cytokines such as IL-6, thus exerting an anti-radiation effect. P53/TLR2 modulator-1 shows significant anti-radiation activity against both AHH-1 cells and HUVECs. It can also increase the survival rate of C57BL/6J mice irradiated with a lethal dose of radiation and reduce the damage to their hematopoietic system, the villous structure of the small intestine, and the spleen caused by radiation. P53/TLR2 modulator-1 can be used in the research of radiation injury-related diseases .
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Cat. No.: HY-P5642
CAS No.: 536757-16-1
Synonyms: RC-101
Retrocyclin-101 (RC-101) is a synthetic cyclic θ-defensin, a broad-spectrum antimicrobial peptide with anti-pathogen (covering viruses, bacteria and fungi) activity and anti-inflammatory activity. Retrocyclin-101 exhibits significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus and others. Retrocyclin-101 inhibits TLR4 and TLR2-mediated signal transduction and reduces pro-inflammatory cytokine expression .
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Cat. No.: HY-174526
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human TLR2 mRNA encodes the human toll like receptor 2 (TLR2) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 is thought to promote apoptosis in response to bacterial lipoproteins.
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Cat. No.: HY-P73589
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TLR2; CD282; Toll Like Receptor 2; Toll/Interleukin-1 Receptor-Like protein 4; Toll-Like Receptor 2; Toll-Like Receptor; TIL4; CD282 Antigen
Species:  
Rat
Source:  
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Cat. No.: HY-P73590Y
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TLR2; CD282; Toll Like Receptor 2; Toll/Interleukin-1 Receptor-Like protein 4; Toll-Like Receptor 2; Toll-Like Receptor; TIL4; CD282 Antigen
Species:  
Source:  
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Cat. No.: HY-P86659
Synonyms: Toll-like receptor 2; Toll like receptor 2; Toll like receptor 2 precursor; Toll-like receptor 2; TLR 2; TLR-2; Toll/interleukin-1 receptor-like protein 4; CD282 antigen; CD282; TIL 4; TIL4; TLR2_HUMAN; Toll/interleukin 1 receptor like 4; Toll/interleukin 1 receptor like protein 4; Toll/interleukin receptor like protein 4.

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-P82187
Synonyms: Toll-Like Receptor 2; TLR2; CD282; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Mouse

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Cat. No.: HY-P82187A
Synonyms: Toll-Like Receptor 2; TLR2; CD282; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Mouse

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Cat. No.: HY-184285
Research Areas:  

Inflammation/Immunology

TLR2 antagonist-2 is a selective TLR2 antagonist with an IC50 of 0.94 μM. TLR2 antagonist-2 inhibits TLR1/2 and TLR2/6 heterodimers. TLR2 antagonist-2 is applicable to the research of inflammatory diseases .
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Cat. No.: HY-P5642A
Synonyms: RC-101 TFA
Retrocyclin-101 (RC-101) TFA is an artificially synthesized, cyclic-structured θ-defensin, a broad-spectrum agent with antimicrobial (covering viruses, bacteria, and fungi) activity and anti-inflammatory activity. Retrocyclin-101 TFA can inhibit the serine protease activity of ZIKV NS2B-NS3, with an IC50 of 7.20 μM. Retrocyclin-101 TFA has significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus, etc. Retrocyclin-101 TFA inhibits the signal transduction mediated by TLR4 and TLR2, reducing the expression of pro-inflammatory cytokines .
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