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Results for "

TPA (Standard)

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18739R
    Phorbol 12-myristate 13-acetate (Standard)

    PMA (Standard); TPA (Standard); Phorbol myristate acetate (Standard)

    		 PKC SphK NF-κB Reference Standards Inflammation/Immunology
    Phorbol 12-myristate 13-acetate (PMA; TPA; Phorbol myristate acetate) (Standard) is the analytical standard of Phorbol 12-myristate 13-acetate. This product is intended for research and analytical applications.
    Phorbol 12-myristate 13-acetate (Standard)
  • HY-13772R
    Valrubicin (Standard)

    AD-32 (Standard)

    		 Reference Standards PKC Antibiotic Inflammation/Immunology Cancer
    Valrubicin (Standard) is the analytical standard of Valrubicin. This product is intended for research and analytical applications. Valrubicin is a chemotherapy agent, inhibits TPA-and PDBu-induced PKC activation with IC50s of 0.85 and 1.25 μM, respectively, and has antitumor and antiinflammatory activity.
    Valrubicin (Standard)
  • HY-I0508R
    Phthalic acid (Standard)

    		Biochemical Assay Reagents Reference Standards Reactive Oxygen Species (ROS) Estrogen Receptor/ERR Endocrinology
    Phthalic acid (Standard) is the analytical standard of Phthalic acid. This product is intended for research and analytical applications. Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells .
    Phthalic acid (Standard)
  • HY-100983R
    Protein kinase inhibitor H-7 dihydrochloride (Standard)

    		Reference Standards PKC Cancer
    Protein kinase inhibitor H-7 (dihydrochloride) (Standard) is the analytical standard of Protein kinase inhibitor H-7 (dihydrochloride). This product is intended for research and analytical applications. Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .
    Protein kinase inhibitor H-7 dihydrochloride (Standard)
  • HY-B1231R
    Heptaminol hydrochloride (Standard)

    RP-2831 hydrochloride (Standard)

    		 Adrenergic Receptor Reference Standards Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .
    Heptaminol hydrochloride (Standard)
  • HY-N0886R
    Aloin B (Standard)

    Isobarbaloin (Standard)

    		 Reference Standards Virus Protease SARS-CoV Infection Metabolic Disease Cancer
    Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .
    Aloin B (Standard)

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