Tubeimoside II (Standard)
Tubeimoside II (Standard) (Tubeimoside-B (Standard)) is the analytical standard of Tubeimoside II (HY-N0891). This product is intended for research and analytical applications. Tubeimoside II is an orally active triterpenoid saponin and antiviral agent that binds to PACT/PRKRA with Kd values of 5.37 μM and 133.1 μM, respectively. Tubeimoside II inhibits oxidase-dependent EGFR activation and reduces TGF-β1-induced oxidative stress. Tubeimoside II activates the RIG-I signaling pathway and increases IFN-β secretion. Tubeimoside II suppresses TPA-induced ear edema, mouse sarcoma 180 growth, and TPA-induced skin tumor formation. Tubeimoside II exerts broad-spectrum antiviral activity against SARS-CoV-2, HCoV-OC43, and IAV-H1N1/FM1. Tubeimoside II can be used in research related to retinoblastoma, respiratory viral infections, skin tumors, and sarcoma 180.
For research use only. We do not sell to patients.
- CAS No.: 115810-12-3
- Formula: C63H98O30
- Molecular Weight:1335.43
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 115810-12-3
-
Molecular Weight 1335.43
-
Formula C63H98O30
-
SMILES
OC[C@H]1O[C@](O[C@H]2[C@@H](O)C[C@@]3(C)[C@](CC[C@]4(C)[C@]3([H])CC=C5[C@@]4(C)C[C@@H](O)[C@]67[C@@]5([H])CC(C)(C)CC6)([H])[C@@]2(CO)C)([H])[C@@](O[C@@]8([H])[C@H](O)[C@@H](O)[C@](OC(C[C@](O)(C)CC(O[C@]9([H])[C@@H](O[C@@]%10([H])[C@H](O)[C@@H](O)[C@H](O)CO%10)[C@@H](O)[C@@](O[C@]%11([H])[C@@H](O)[C@@H](O)CO[C@@]%11([H])OC7=O)([H])O[C@H]9C)=O)=O)([H])CO8)([H])[C@@H](O)[C@@H]1O
-
Synonyms
Tubeimoside-B (Standard)
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Chen Y, et al. Tubeimoside II inhibits TGF-β1-induced metastatic progression of human retinoblastoma cells through suppressing redoxosome-dependent EGFR activation. Chem Biol Interact. 2021;335:109367. [Content Brief]
[2]. Liu X, et al. A new approach to discovering a broad-spectrum anti-respiratory virus drug: Tubeimoside II modulates host factor PACT to potentiate the RIG-I antiviral pathway. Acta Pharm Sin B. 2026;16(5):3109-3127. [Content Brief]
[3]. Yu TX, et al. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin. 2001;22(5):463-468. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tubeimoside II (Standard) Related Classifications
HY-N0891R Related Classifications
Powered by Bioz
- Tubeimoside II (Standard)
- 115810-12-3
- Tubeimoside-B (Standard)
- Reference Standards
- EGFR
- TGF-β Receptor
- RIG-I-like receptor (RLR)
- SARS-CoV
- human PACT/PRKRA
- retinoblastoma
- human retinoblastoma Y-79 cells
- SARS-CoV-2
- RIG-I signaling pathway
- respiratory viral infections
- transplantable mouse sarcoma 180
- skin neoplasms
- human retinoblastoma WERI-Rb-1 cells
- Inhibitor
- inhibitor
- inhibit