26 Results for "

TRP-1

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "TRP-1" in MCE Product Catalog:

Cat. No.: HY-D0168
CAS No.: 504-15-4
Synonyms: 3,5-Dihydroxytoluene
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases [1] .
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Cat. No.: HY-N2413
CAS No.: 60546-10-3
Gomisin D is an orally active lignan that binds to PDGFRβ with a Kd of 10 μM. By targeting PDGFRβ to regulate signaling pathways, Gomisin D inhibits the activation and proliferation of hepatic stellate cells and promotes their apoptosis, thereby ameliorating hepatic fibrosis. Gomisin D exhibits multiple activities such as photoprotection, antimelanogenesis, antioxidant effects, and hypoglycemic activity. Gomisin D can be used in studies related to diabetes, Alzheimer's disease, and hepatic fibrosis [1] .
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Cat. No.: HY-N2983
CAS No.: 32884-36-9
Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis [1] .
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Cat. No.: HY-134046
CAS No.: 10391-08-9
Synonyms: Isodocarpin
(-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA [1].
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Cat. No.: HY-N10016
CAS No.: 132741-56-1
Chlorogenic acid butyl ester, a caffeoylquinic acid, is a potent melanogenesis inhibitor. Chlorogenic acid butyl ester inhibits the expression of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosinerelated protein 1 (TRP-1), and TRP-2. Chlorogenic acid butyl ester also shows antioxidant activity [1].
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Cat. No.: HY-N0113A
CAS No.: 62493-39-4
Synonyms: Ordenina sulfate; Peyocactine sulfate
Hordenine sulfate (Ordenina sulfate) is an active compound extracted from malted barley that has melanin-inhibiting activity. Hordenine sulfate significantly reduced melanin content and reduced intracellular cAMP levels. Hordenine sulfate inhibits the expression of proteins related to melanogenesis, including microblind transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2. Therefore, Hordenine sulfate can be used as an active ingredient to inhibit pigmentation [1].
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Cat. No.: HY-P73568
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; TRP-1; TYRP1; CAS2
Species:  
Source:  
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Cat. No.: HY-P11636A
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

TRP-1(106-130) acetate is a peptide sequence derived from tyrosinase-related protein 1 (TRP-1), which can be used to specifically activate and amplify T cells that recognize this antigen sequence [1].
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Cat. No.: HY-P11636
CAS No.: 2844316-27-2
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

TRP-1(106-130) is a peptide sequence derived from tyrosinase-related protein 1 (TRP-1), which can be used to specifically activate and amplify T cells that recognize this antigen sequence [1].
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Cat. No.: HY-P82582
Synonyms: CAS2; CATB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-RS18847
Research Areas:  

Others

Tyrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tyrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS15104
Research Areas:  

Others

TRPC1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS15119
Research Areas:  

Others

TRPS1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19749
Research Areas:  

Others

Trps1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trps1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS11245
Research Areas:  

Others

PRSS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRSS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0637AR
CAS No.: 4049-38-1
Synonyms: (±)-Huazhongilexone (Standard); Dihydroluteolin (Standard)
3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases [1] .
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Cat. No.: HY-N10437
CAS No.: 1281766-66-2
Synonyms: 6-O-Acetylnimbandiol
6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research [1].
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Cat. No.: HY-RS11645
Research Areas:  

Others

RANBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RANBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P81502
Synonyms: CAS2; CATB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP; DHICA oxidase

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81502A
Synonyms: CAS2; CATB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP; DHICA oxidase

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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