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TRP1 Antibody (YA2327)

(Synonyms: CAS2; CATB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP)
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TRP1 Antibody (YA2327) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TRP1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Conjugation:
    Non-conjugated
  • TRP1 Antibody (YA2327) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:50-1:100 1:50

Product Details

Description

TRP1 Antibody (YA2327) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TRP1.

  • Host Rabbit
  • Clonality Recombinant, Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 75 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 61 kDa
Species Reactivity Database

Entrez Gene: 7306 Human

SwissProt: P17643 Human

Immunogen

A synthesized peptide derived from human TRP1 aa500-537/537.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3104683

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TRP1 plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin[1][2][3][4].

  • Subcellular Localization

    Melanosome membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:pigment cells

  • Subunit

    Monomer (PubMed:28661582). Interacts with ATP7A (By similarity) (PubMed:28661582). Interacts with SLC45A2 (By similarity)

  • SwissProt ID

    P17643

  • Gene ID
    7306 [NCBI]
  • Synonyms

    CAS2; CATB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP

  • Research Field

    Tags & Cell Markers

TRP1 Antibody (YA2327) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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