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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Thalidomide-4-OH
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Thalidomide-4-OH" in MCE Product Catalog:
Synonyms: Cereblon ligand 2; E3 ligase Ligand 2
Target:
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Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
Cat. No.: HY-W674436
CAS No.: 2357105-36-1
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(S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
Cat. No.: HY-103596R
CAS No.: 5054-59-1
Synonyms: Cereblon ligand 2 (Standard); E3 ligase Ligand 2 (Standard)
Research Areas:
Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
Cat. No.: HY-W090651
CAS No.: 1957235-70-9
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Thalidomide-4-OH-(S)-CH3 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-4-OH-(S)-CH3 can be linked to a target protein ligand via a linker to form a PROTAC.
Cat. No.: HY-174087
CAS No.: 3071165-50-6
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Thalidomide-4-OH-C11-OH is an E3 Ligase Ligand-Linker Conjugate, which is composed of Thalidomide-4-OH (HY-103596) and the corresponding Linker. Thalidomide-4-OH-C11-OH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules, such as PROTAC GPX4 degrader-4 (HY-174086) .
Cat. No.: HY-168964
CAS No.: 1957235-61-8
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Ethanolamine-Thalidomide-4-OH is an E3 Ligase Ligand-Linker Conjugate composed of an CRBN ligand (HY-103596) and a linker (HY-Y0524), and can be used for synthesis of PROTACs (eg: PROTAC BTK Degrader-13 (HY-168963)) .
Cat. No.: HY-42771
CAS No.: 1950635-36-5
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Thalidomide-4-O-CH2-COO(t-Bu) is t-Bu modified Thalidomide (HY-14658), which is the final step intermediate in the synthesis of Thalidomide-4-OH (HY-123096). Thalidomide-4-O-CH2-COO(t-Bu) acts as a Cereblon ligand to recruit CRBN proteins. The t-Bu protecting group at the end of Thalidomide-4-O-CH2-COO(t-Bu) can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-O-CH2-COO(t-Bu) is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules.
Cat. No.: HY-176181
CAS No.: 3023389-80-9
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Thalidomide-4-OH-PEG4-OTs is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based CRBN ligand (HY-103596) and 4-unit PEG linker (HY-176182). Thalidomide-4-OH-PEG4-OTs can be used for synthesis of PROTAC STING degrader-4 (HY-176180) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
