3071165-50-6
3071165-50-6
Chemical Structure
Thalidomide-4-OH-C11-OH
- CAS. Nr.: 3071165-50-6
- Formula:C24H32N2O6
- Molecular Weight:444.52
SMILES: O=C1N(C(C2=C(C=CC=C21)OCCCCCCCCCCCO)=O)C3CCC(NC3=O)=O
Biological Activity: Thalidomide-4-OH-C11-OH is an E3 Ligase Ligand-Linker Conjugate, which is composed of Thalidomide-4-OH (HY-103596) and the corresponding Linker. Thalidomide-4-OH-C11-OH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules, such as PROTAC GPX4 degrader-4 (HY-174086)[1].
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Thalidomide-4-OH-C11-OH | Thalidomide-4-OH-C11-OH is an E3 Ligase Ligand-Linker Conjugate, which is composed of Thalidomide-4-OH (HY-103596) and the corresponding Linker. Thalidomide-4-OH-C11-OH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules, such as PROTAC GPX4 degrader-4 (HY-174086). | |||||||||||||||||||||
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