5054-59-1

Thalidomide-4-OH Chemical Structure
5054-59-1

Chemical Structure

Thalidomide-4-OH

Synonym(s): Cereblon ligand 2; E3 ligase Ligand 2

  • CAS No.: 5054-59-1
  • Formula:C13H10N2O5
  • Molecular Weight:274.23

IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

InChIKey: XMPJICVFSDYOEG-UHFFFAOYSA-N

SMILES: OC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O

Biological Activity: Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-103596
Thalidomide-4-OH 99.62% Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
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HY-103596R
Thalidomide-4-OH (Standard) ≥98% Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
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(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References