5054-59-1

Thalidomide-4-OH Chemical Structure
5054-59-1

Chemical Structure

Thalidomide-4-OH

Synonym(s): Cereblon ligand 2; E3 ligase Ligand 2

  • CAS No.: 5054-59-1
  • Formula:C13H10N2O5
  • Molecular Weight:274.23

IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

InChIKey: XMPJICVFSDYOEG-UHFFFAOYSA-N

SMILES: OC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O

Biological Activity: Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-103596
Thalidomide-4-OH 99.62% Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
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HY-103596R
Thalidomide-4-OH (Standard) ≥98% Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
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