5054-59-1
Chemical Structure
Thalidomide-4-OH
Synonym(s): Cereblon ligand 2; E3 ligase Ligand 2
- CAS No.: 5054-59-1
- Formula:C13H10N2O5
- Molecular Weight:274.23
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione
InChIKey: XMPJICVFSDYOEG-UHFFFAOYSA-N
SMILES: OC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].
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Thalidomide-4-OH | 99.62% | Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Thalidomide-4-OH (Standard) | ≥98% | Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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